Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
40 participants
INTERVENTIONAL
2022-09-01
2026-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Adsorber Group
Surgery with CPB will be performed according to institutional standards, depending on indications and surgical preferences.
For the intervention group (adsorber-group), the CytoSorb adsorber will be installed on the CPB machine in a parallel circuit to the body circulation. The flow through the filter will be driven by a roller pump with 300-400 ml.min-1.
CytoSorb Adsorber
Polymer based adsorber system for the elimination of cytokines
Control
The control group (no-adsorber group) will be treated similarly, but no filter circuit will be installed.
No interventions assigned to this group
Interventions
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CytoSorb Adsorber
Polymer based adsorber system for the elimination of cytokines
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Age \< 18 years#
* Receiving antileukocyte drugs
* Receiving TNF-α Blockers, immunosuppressive drugs (e.g. tocilizumab)
* DCD
* Ex-vivo perfusion
18 Years
ALL
No
Sponsors
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Medical University of Vienna
OTHER
Responsible Party
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Dr. Martin Bernardi
Principal Investigator
Principal Investigators
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Martin H. Bernardi, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Medical University of Vienna
Locations
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Divison of Cardiac Thoracic Vascular Anaesthesia and Intensive Care, Medical University of Vienna
Vienna, Vienna, Austria
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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1933/2021
Identifier Type: -
Identifier Source: org_study_id
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