Minimal Extracorporeal Circuits (MECC) in Cardiac Surgery Procedures

NCT ID: NCT01306903

Last Updated: 2013-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The standard heart-lung machine is a major trigger of systemic inflammatory reactions, hemodilution, coagulopathy or organ failure. The strict reduction of blood-artificial surface and blood-air contact might represent meaningful improvements of the extracorporeal technology with respect to organ preservation.

The aim of this study is the evaluation of potential differences between a minimal extracorporeal circuit (MECC) and a conventional cardiopulmonary bypass (MOPS) system.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postoperative Bloodloss

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

MECC

Minimal extracorporeal circuit

Group Type EXPERIMENTAL

MECC

Intervention Type DEVICE

Minimized extracorporeal circulation

MOPS

Group Type PLACEBO_COMPARATOR

MOPS

Intervention Type DEVICE

Modified and optimized perfusion system Frankfurt

Super MOPS

Group Type PLACEBO_COMPARATOR

Super MOPS

Intervention Type DEVICE

Super modified and optimized perfusion system Frankfurt

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MECC

Minimized extracorporeal circulation

Intervention Type DEVICE

MOPS

Modified and optimized perfusion system Frankfurt

Intervention Type DEVICE

Super MOPS

Super modified and optimized perfusion system Frankfurt

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* extracorporeal circulation
* age \> 18 years old
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Arndt-H. Kiessling

PI

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Arndt H Kiessling, MD

Role: PRINCIPAL_INVESTIGATOR

Goethe University Frankfurt

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Goethe University Hospital

Frankfurt, , Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Mini-ECC001AHK

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Thrombin in Cardiac Surgery
NCT04762576 UNKNOWN