Revascularisation of Autotransplanted Teeth

NCT ID: NCT05267249

Last Updated: 2022-03-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-06

Study Completion Date

2022-02-15

Brief Summary

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Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection

Note: The study was registered on Clinicaltrials.gov after termination of study.

Detailed Description

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Conditions

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Endodontic Disease Pulp Canal Obliteration

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Autotransplantation

Autotransplantation and apicoectomy of mature teeth

Group Type EXPERIMENTAL

Autotransplantation and Apicoectomy

Intervention Type PROCEDURE

Autotransplantation of a mature teeth with simultaneous extra-oral root-end resectoin

Interventions

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Autotransplantation and Apicoectomy

Autotransplantation of a mature teeth with simultaneous extra-oral root-end resectoin

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Male and female consenting and judicious young people and adults
* Written consent of the participant and, if applicable, of the legal guardian after education
* Planned tooth transplantation with advanced or completed root growth

Exclusion Criteria

* Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw)
* Current or past antiresorptive therapy with bisphosphonates
* Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases
* Acute gingivitis or advanced periodontitis
* Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors)
* heavy smokers (\> 10 per day)
* Acute or chronic infections (osteomyelitis) at the surgical site
* metabolic diseases (diabetes, hyperparathyroidism, osteomalacia)
* Severe kidney dysfunction, severe liver disease
* Patients with high-dose corticosteroid therapy
* prolonged corticosteroid or radiotherapy in the oral cavity
* autoimmune diseases
* Pregnant or breastfeeding women
Minimum Eligible Age

12 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Graz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Petra Rugani, DDS

Role: PRINCIPAL_INVESTIGATOR

Medical University of Graz

Locations

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Medical University of Graz

Graz, Styria, Austria

Site Status

Countries

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Austria

References

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Jakse N, Ruckenstuhl M, Rugani P, Kirnbauer B, Sokolowski A, Ebeleseder K. Influence of Extraoral Apicoectomy on Revascularization of an Autotransplanted Tooth: A Case Report. J Endod. 2018 Aug;44(8):1298-1302. doi: 10.1016/j.joen.2018.04.016. Epub 2018 Jun 20.

Reference Type BACKGROUND
PMID: 29935869 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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ResectTX

Identifier Type: -

Identifier Source: org_study_id

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