Evaluation of Bone Behavior in Maxillary Post-extractive Sites Treated With Guided Bone Regeneration (G.B.R.) Techniques in Alveolar Socket Preservation (A.S.P.) Procedures With Different Autologous and Heterologous Biomaterials.
NCT ID: NCT07269990
Last Updated: 2025-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE1
30 participants
INTERVENTIONAL
2023-07-03
2026-05-31
Brief Summary
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The results of bone loss induced aesthetic and functional difficulties in achieving surgical and prosthetic rehabilitation of the right dental implant.
Bone loss can be restored with autologous bone grafts and in large bone atrophy of the jaws require complex surgical techniques such as vascularized bone transplantation.
As an alternative to the reconstruction of the maxillary tissue, several surgical techniques have been promoted to prevent or minimize bone resorption through market biomaterials with or without the patient's autologous bone.
To reduce or counteract biological bone resorption, surgeons have promoted alveolar cavity preservation procedures (ASP) with autologous or heterologous graft materials.
Recently, several studies have been published to evaluate the use of demineralized dentin material derived from the extracted tooth to obtain new bone in the maxillary post-extraction site.
The aim of the study is to compare different types of biomaterials 4 months after application through the use of the alveolar socket preservation technique.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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compare different types of biomaterials 4 months after application through the use of ASP Group 1
compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 1
compare different types of biomaterials 4 months after application through the use of ASP Group 2
Comparison of different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 2
compare different types of biomaterials 4 months after application through the use of ASP Group 3
Comparison different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 3
compare different types of biomaterials 4 months after application through the use of ASP Group 4
The aim is to compare different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 4
compare different types of biomaterials 4 months after application through the use of ASP Group 5
The aim is to compare different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 5
Interventions
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compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 1
Comparison of different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 2
Comparison different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 3
The aim is to compare different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 4
The aim is to compare different types of biomaterials 4 months after application through the use of ASP
The aim is to compare different types of biomaterials 4 months after application through the use of ASP in Group 5
Eligibility Criteria
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Inclusion Criteria
* Diagnosis of tooth extraction in the upper or lower jaw.
* Preservation procedures necessary to preserve jawbone volume with Guided
* Bone regeneration with autologous or heterologous biomaterials.
Exclusion Criteria
* Patients with conditions that may interfere with the evaluation or confound the results. (e.g. they are already taking treatments)
* Patients with refusal to participate, inability to provide data, or at high risk of loss to follow-up.
* Patients with neoplastic pathologies.
* Patients with Radio-Chemo therapies.
18 Years
90 Years
ALL
Yes
Sponsors
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University of Foggia
OTHER
Responsible Party
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Filiberto Mastrangelo
Clinical Professor, Principal Investigator
Locations
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University of Foggia
Foggia, Foggia, Italy
Countries
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Other Identifiers
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7-CE-2023
Identifier Type: -
Identifier Source: org_study_id