Effect of Cranberry Extract on the Urinary System

NCT ID: NCT05260554

Last Updated: 2022-03-02

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-01-26
• Study Completion Date: 2022-02-18

Brief Summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Detailed Description

This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

Conditions

Urinary Tract Disease; Cystitis; Antibiotic Reaction

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

using fosfomycin

The patients in this group; have been prescribed fosfomycin for 7 days (3 doses, two days apart).

Fosfomycin

Intervention Type: DRUG

In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

using cranberry extract

The patients in this group; took 7 days (1 tablet each day) of cranberry tablets.

Cranberry

Intervention Type: DIETARY_SUPPLEMENT

In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

Interventions

Fosfomycin

In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

Intervention Type: DRUG

Cranberry

In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

Intervention Type: DIETARY_SUPPLEMENT

Other Intervention Names

monurol

Eligibility Criteria

Inclusion Criteria

• Older than 18
• who have urinary tract inflammation
• who haven't kidney dissease previous

Exclusion Criteria

• Younger than 18
• Who have kidney inflammation
• Pregnant patients
• Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Kırklareli University

OTHER

Sponsor Role: lead

Responsible Party

Oya Guven, MD

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Oya Guven

Role: STUDY_DIRECTOR

Kırklareli University

Locations

Oya Guven, MD

Kırklareli, Center, Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Gray M. Are cranberry juice or cranberry products effective in the prevention or management of urinary tract infection? J Wound Ostomy Continence Nurs. 2002 May;29(3):122-6. doi: 10.1067/mjw.2002.124016. No abstract available.

Reference Type: RESULT

PMID: 12011903 (View on PubMed)

Other Identifiers

Kırklareli University

Identifier Type: -

Identifier Source: org_study_id