Effect of Intensive Cognitive Rehabilitation on Cognitive, Motor, and Language Functional Networks in Subacute Stroke Patient

NCT ID: NCT05254964

Last Updated: 2023-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-01

Study Completion Date

2023-02-28

Brief Summary

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Altered brain networks, including cognitive, motor, and language networks, are investigated by intensive cognitive rehabilitation in subacute stroke patients.

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intensive cognitive rehabilitation group

Participants receive intensive cognitive rehabilitation for 20 hours for 4 weeks.

Group Type EXPERIMENTAL

Cognitive rehabilitation

Intervention Type PROCEDURE

Intensive cognitive rehabilitation by cognitive therapist for 1 hour on every working 20 days (4 weeks) during the subacute stroke phase

Interventions

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Cognitive rehabilitation

Intensive cognitive rehabilitation by cognitive therapist for 1 hour on every working 20 days (4 weeks) during the subacute stroke phase

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 19 to 80 years
* Patients with subacute stroke within 2 weeks of onset
* First-ever stroke
* Supratentorial stroke
* Less than 8 SAFE (shoulder abduction, finger extension) points
* Less than 35 FMA Upper scores
* MEP (motor evoked potential) negative
* Not more than 24 K-MMSE (Korean Mini-Mental State Examination) score

Exclusion Criteria

* Difficult to communicate due to severe language impairment.
* Accompanied by an existing serious neurogenic disease
* Existing significant psychiatric disorders such as major schizophrenia, bipolar disorder
* If there are difficulties in conducting the research
* Any patients who are judged by the investigator to be difficult to participate in this study
* Patients with contraindicated MRI scans
Minimum Eligible Age

19 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Yun-Hee Kim

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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2021-12-019

Identifier Type: -

Identifier Source: org_study_id

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