Early Vitrectomy for Endophthalmitis After Cataract Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

11 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-02

Study Completion Date

2022-01-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness. Acute post-operative endophthalmitis usually presented within 6 weeks of intraocular procedure and diagnosis is confirmed by clinical examination and by the aid of B-scan ultrasonography.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Anterior Segment Changes After Phacoemulsification in Cataractous Eyes with Shallow Anterior Chamber

NCT06745596

Cataract

COMPLETED NA

Stepped Surgery in Uveitic Cataract: A Novel Approach to a Quiet Eye

NCT04931277

Outcome of Stepped Cataract Surgery in Uveitis

COMPLETED NA

Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT

NCT06524661

Glaucoma

COMPLETED

Corneal Endothelial Cell Loss After Phacoemulsification Compared With Extracapsular Cataract Extraction

NCT03262285

Senile Cataract

COMPLETED

IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls

NCT04334473

Glaucoma Cataract

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

There is no consensus regarding the timing of vitrectomy in cases with endophthalmitis after cataract surgery. The Endophthalmitis Vitrectomy Study concluded that vitrectomy should be preserved for cases with only light perception. The advances in posterior segment machines and small gauge cannulas decrease the incidence of intra-operative complications and encourage for early intervention in cases with endophthalmitis after primary cataract surgery.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Endophthalmitis Cataract Vitreous Detachment Retinal Detachment

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Endophthalmitis after primary cataract surgery.

Cases diagnosed as acute post-operative endophthalmitis after primary cataract surgery.

Early 23-gauge pars-plana vitrectomy

Intervention Type PROCEDURE

pars-plana vitrectomy for management of acute post-operative endophthalmitis.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Early 23-gauge pars-plana vitrectomy

pars-plana vitrectomy for management of acute post-operative endophthalmitis.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Acute onset endophthalmitis within 6 weeks after primary cataract surgeries.
* Patients had undergone early pars-plana vitrectomy within 48 hours of their confirmed diagnosis.

Exclusion Criteria

* Patients were diagnosed as endogenous or chronic endophthalmitis.
* Patients with a previous history of rupture globe surgery or trauma.
* Patients who didn't complete the follow up period.

Minimum Eligible Age

3 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No