Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases

NCT ID: NCT05215444

Last Updated: 2023-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

42 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2021-06-30

Brief Summary

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study of some laboratory and clinical findings which may show the severity of aluminium phosphide toxicity and the need of the cases to be admitted to ICU

Detailed Description

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aluminium phosphide poisoning is a major cause of death in intoxicated and suicidal cases since there is no antidote and there is no specific investigation for it so there is a need for further study to identify the cause of death and the most specific investigation in the case of AlP toxicity

Conditions

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Aluminum Phosphide Poisoning

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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survivors

some prognostic factors

Intervention Type DIAGNOSTIC_TEST

cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

non survivors

some prognostic factors

Intervention Type DIAGNOSTIC_TEST

cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

Interventions

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some prognostic factors

cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. History of exposure or intake of Aluminum phosphide.
2. Clinical picture of Acute Aluminum phosphide poisoning including severe vomiting, hypotension, abdominal pain, cardio-pulmonary distress.
3. Cases of the age of 15 to 45 years old

Exclusion Criteria

\- 1. Cases with an unclear history. 2. History of co-morbidities or systemic diseases because of the possibility of misleading laboratory results.

3\. History of co-ingestion of drugs or another poison.
Minimum Eligible Age

15 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zagazig University

OTHER_GOV

Sponsor Role lead

Responsible Party

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shymaa mohamed nasrallah abdulrhman

demonstrator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Medicine Zagazig University

Zagazig, Sharqia Province, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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6665

Identifier Type: -

Identifier Source: org_study_id

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