Collaborative Quality Improvement (C-QIP) Study

NCT ID: NCT05196659

Last Updated: 2026-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

410 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-09

Study Completion Date

2024-12-31

Brief Summary

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The overarching goal of this study is to develop, implement, and evaluate the effect of a collaborative quality improvement (C-QIP) intervention (consisting of non-physician health workers, text messages for a healthy lifestyle, and a clinical decision support system) on processes of care and clinical outcomes among individuals with previous cardiovascular disease in India.

Detailed Description

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Specific objectives of this study are:

1. To describe current practices, context, challenges, and opportunities regarding chronic management of cardiovascular disease from the patient, caregiver, provider, and health administrator perspectives in India.
2. To assess the transferability of components of internationally successful multifaceted quality improvement strategies and chronic care models to the Indian healthcare context.
3. To conduct a pilot study to assess the acceptability, feasibility, and implementation fidelity of the C-QIP strategy among individuals with cardiovascular disease attending out-patient clinics in India.
4. Among individuals with cardiovascular disease, evaluate the effect of C-QIP strategy on processes of care and clinical outcomes, health-related quality of life, and costs at 1 year compared with usual care.

Conditions

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Coronary Heart Disease Ischemic Stroke Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Individual randomized parallel-group feasibility trial
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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CONTROL Group

* Regular current system of care
* Treating physicians provided current cardiovascular disease management guidelines
* Patients provided a leaflet (printed information) on healthy lifestyle

Group Type NO_INTERVENTION

No interventions assigned to this group

INTERVENTION Group

1. Electronic Health Record-Decision Support Software (EHR-DSS):

* Electronic patient health record storage
* Management prompts to the clinical team (following algorithms)
* Structured follow-up schedule with automatic reminders to patients, clinical team, and non-physician health worker
2. Non-physician health worker-led continuity of care:

\- individually tailored follow-up and guidance regarding treatment adherence as well as help in resolving issues related to access, convenience, cost of care, and equity
3. Text-message based reminders for a healthy lifestyle
4. Patient diary containing visual assessment tool for adherence to medication (VITA) and reinforcement tool for lifestyle modification
5. Quarterly audit and feedback to the clinical team

Group Type ACTIVE_COMPARATOR

Integrated comprehensive cardiovascular disease management

Intervention Type BEHAVIORAL

1. Electronic Health Record-Decision Support Software (EHR-DSS):

* Electronic patient health record storage
* Management prompts to the clinical team (following algorithms)
* Structured follow-up schedule with automatic reminders to patients, clinical team, and non-physician health worker
2. Non-physician health worker-led continuity of care:

\- individually tailored follow-up and guidance regarding treatment adherence as well as help in resolving issues related to access, convenience, cost of care, and equity
3. Text-message based reminders for a healthy lifestyle
4. Patient diary containing visual assessment tool for adherence to medication (VITA) and reinforcement tool for lifestyle modification
5. Quarterly audit and feedback to the clinical team

Interventions

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Integrated comprehensive cardiovascular disease management

1. Electronic Health Record-Decision Support Software (EHR-DSS):

* Electronic patient health record storage
* Management prompts to the clinical team (following algorithms)
* Structured follow-up schedule with automatic reminders to patients, clinical team, and non-physician health worker
2. Non-physician health worker-led continuity of care:

\- individually tailored follow-up and guidance regarding treatment adherence as well as help in resolving issues related to access, convenience, cost of care, and equity
3. Text-message based reminders for a healthy lifestyle
4. Patient diary containing visual assessment tool for adherence to medication (VITA) and reinforcement tool for lifestyle modification
5. Quarterly audit and feedback to the clinical team

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Participants should be:

* age ≥18 years, both sexes
* confirmed diagnosis of cardiovascular disease (ischemic heart disease, stroke, or heart failure irrespective of ejection fraction)
* able to provide written informed consent.

Exclusion Criteria

* pregnant women
* those with any serious or uncontrolled medical condition (e.g., cancer) that may restrict the patient to come for follow-up.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Public Health Foundation of India

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kavita Singh, PhD

Role: PRINCIPAL_INVESTIGATOR

Public Health Foundation of India

Locations

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SDM College of Medical Sciences and Hospital

Dharwad, Karnataka, India

Site Status

All India Institute of Medical Sciences (AIIMS)

New Delhi, National Capital Territory of Delhi, India

Site Status

GB Pant Hospital

New Delhi, New Delhi, India

Site Status

Sir Ganga ram Hospital

New Delhi, New Delhi, India

Site Status

Countries

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India

References

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Singh K, Nikhare K, Gandral M, Aithal K, Patil SG, Mp G, Gupta M, Madan K, Sawhney JPS, Ali K, Kondal D, Jindal D, Mendenhall E, Patel SA, Narayan KMV, Tandon N, Roy A, Huffman MD, Prabhakaran D. Rationale, Design and Baseline Characteristics of a Randomized Controlled Trial of a Cardiovascular Quality Improvement Strategy in India: The C-QIP Trial. Am Heart J. 2024 Oct;276:83-98. doi: 10.1016/j.ahj.2024.07.008. Epub 2024 Jul 20.

Reference Type DERIVED
PMID: 39033994 (View on PubMed)

Other Identifiers

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RA1055

Identifier Type: -

Identifier Source: org_study_id

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