Office-based Validation of the JVPHome

NCT ID: NCT05193864

Last Updated: 2022-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-29

Study Completion Date

2023-01-03

Brief Summary

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The JVPHome is a novel medical device that utilizes machine vision in order to facilitate assessment of jugular venous pressure (JVP) height relative to the sternal angle with the ultimate goal of enabling remote JVP monitoring. The current study aims to evaluate the ability of an enhanced version of the JVPHome to enable remote identification of JVP height relative to ultrasound among congestive heart failure (CHF) patients when the device is applied by the study team in the clinic.

Detailed Description

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CHF is a common and devastating health problem estimated to affect upwards of 26 million individuals worldwide. Following an initial hospitalization for heart failure, approximately 25% of patients are readmitted within the first 30 days of discharge. Repeat heart failure hospitalizations are a major burden on both patients and healthcare systems. To date, there is an absence of non-invasive solutions proven to reduce the risk of re-hospitalization for CHF.

The key feature of the physical examination for assessing the volume status of CHF patients is the JVP, which manifests as a biphasic pulsation along the neck. The height of the JVP relative to the sternal angle is a reflection of right atrial pressure, which increases in response to higher pressures transmitted from the left side of the heart. Pathologic elevation of left sided heart pressures can result in fluid congestion in the lungs, which can cause patients to develop shortness of breath and reduced blood oxygen levels. Although a crucial marker of volume status, accurate identification of the JVP can be challenging for physicians due to its pulsations often being subtle.

The JVPHome is a novel medical device designed to facilitate visualization of JVP height relative to the sternal angle through the use of machine vision. The current study aims to evaluate an enhanced version of the JVPHome in a clinic setting when the device is applied to CHF patients by clinicians. Following its application, the JVPHome will be allowed to record a video of the JVP and images will subsequently be transmitted to a secure cloud and undergo analysis with machine vision software. Visualization of the JVP will be facilitated through simultaneous electrocardiographic and pulse oximetry recordings by the JVPHome. Following its application, data is transferred to a secure cloud server for subsequent processing and clinical review.

JVP height of study participants will be concurrently assessed through the use of ultrasound (gold standard). Clinicians that are blinded to ultrasound determined JVP height values will assess JVP height generated by the JVPHome. Analyses will then assess the accuracy of the JVPHome relative to ultrasound and expert clinical assessment.

Conditions

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Congestive Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ambulatory CHF patients

Patients visiting an outpatient CHF clinic

Device: JVPHome and ultrasound

Intervention Type DEVICE

Remote clinician assessment of JVP height using the JVPHome, and ultrasound based assessment of JVP height in the same patients.

Interventions

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Device: JVPHome and ultrasound

Remote clinician assessment of JVP height using the JVPHome, and ultrasound based assessment of JVP height in the same patients.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age \>/= 18 years
* Congestive heart failure diagnosis receiving ongoing treatment
* Able to provide informed consent

Exclusion Criteria

* Conditions which preclude visualization of the JVP, including neck deformity, scarring, and facial hair
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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JVPLabs

UNKNOWN

Sponsor Role collaborator

Eastern Regional Health Authority

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kris Aubrey-Bassler, MD

Role: PRINCIPAL_INVESTIGATOR

Eastern Health

Locations

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Eastern Health

St. John's, Newfoundland and Labrador, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Krista Rideout, MN

Role: CONTACT

(709) 777 2638

Facility Contacts

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Kevin Oram, BSc

Role: primary

Other Identifiers

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335576

Identifier Type: -

Identifier Source: org_study_id

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