Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma

NCT ID: NCT05185544

Last Updated: 2022-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2024-12-31

Brief Summary

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Combining genomics and imageomics to predict the sensitivity of neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Detailed Description

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Conditions

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Sensitivity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Neoadjuvant pemetrexed and cisplatin chemotherapy

Intervention Type OTHER

neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Interventions

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Neoadjuvant pemetrexed and cisplatin chemotherapy

neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 1\. Aged between 18 and 75 years;
* 2\. Lung adenocarcinoma;
* 3\. The patient is able to receive neoadjuvant pemetrexed and cisplatin chemotherapy
* 4 .The patient is able to understand and comply with the study and has provided written informed consent.

Exclusion Criteria

* 1\. Patients with a history of lung surgery;
* 2\. Postoperative pathology showed non-primary lung cancer;
* 3\. Patients with a history of other tumors;
* 4\. Patients with severe complications (coronary heart disease, valvular heart disease, end-stage renal disease, severe liver cirrhosis);
* 5\. Unable to cooperate with the researchers because of dementia or cognitive decline
* 6\. Other situations that are not in conformity with the standards and requirements of this trial.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Zhongshan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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B2021-Zhan

Identifier Type: -

Identifier Source: org_study_id

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