The Effect of TaiChi on Ischemic Burden of Patients With Coronary Heart Disease Complicated With Renal Insufficiency

NCT ID: NCT05178602

Last Updated: 2022-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

142 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-01

Study Completion Date

2024-12-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study focuses on patients with incomplete revascularization combined with renal insufficiency. And since heart and kidney are two organs influence each other, the study take the mechanism of heart and kidney comorbidity and the risk factors of the two organs.As one of the traditional Chinese sports, Tai Chi is an aerobic exercise combineing movements with static postures, which can significantly improve the aerobic endurance of patients with coronary heart disease. In this study, a parallel, randomized controlled study method is used to quantitatively evaluate the myocardial ischemia condition by myocardial perfusion imaging indicators. This study aims to figure out whether the cardiac rehabilitation training program based on Tai Chi has a positive effect on the patients' myocardial ischemic.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Heart Disease (CHD) Renal Insufficiency

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

The experimental group

Routine treatment, and tai Chi exercise,5 times a week

Group Type EXPERIMENTAL

Tai Chi Intervention Group

Intervention Type BEHAVIORAL

Tai Chi intervention group: routine treatment and tai Chi exercise,5 times a week.

The control group

Routine treatment, and cardiac rehabilitation is not mandatory

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Tai Chi Intervention Group

Tai Chi intervention group: routine treatment and tai Chi exercise,5 times a week.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. 30-75 years old, all genders;
2. At least two main vessels or their main branch vessels have obvious stenosis (≥50%) according to the coronary angiography;
3. Received stent implantation and incomplete revascularization (incomplete revascularization: at least one vessel whose a diameter\> 2.0 mm and at least one lesion with a stenosis\> 50%, after PCI);
4. eGFR\<60ml/min·1.73m2;
5. Willing to be treated and followed-up during the specified time of the study;
6. Signed the informed consent approved by the Ethics Committee

Exclusion Criteria

1. Patients with high-risks according to the exercise rehabilitation risks of patients with heart disease by AACVPR;
2. Severe cardiac insufficiency or cardiogenic shock;
3. Combined with severe ventricular arrhythmia, ICD is required;
4. Combined with severe pulmonary hypertension, chronic obstructive pulmonary disease, severe infectious disease, blood system disease, malignant tumor, severe liver damage, etc.;
5. Nervous, mental and motor system diseases;
6. Unwilling to be followed-up.
Minimum Eligible Age

30 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Beijing Anzhen Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Ji Huang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

JI Huang, Doctor

Role: CONTACT

15810291548

Chu Fan, Postgraduate

Role: CONTACT

+8618832070253

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

TaiChi trial

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Exercise Intervention for Pre-frail Elderly
NCT06519695 ACTIVE_NOT_RECRUITING NA