Evaluation of GvHD Damage on Medullary Mesenchymal Stem Cells

NCT ID: NCT05167188

Last Updated: 2023-05-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-14

Study Completion Date

2025-03-31

Brief Summary

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Spontaneous, multicenter, prospective, non-pharmacological study. At the diagnosis of acute or chronic GvHD after HSCT, bone marrow cells will be analysed for MSC content and properties. Bone marrow aspirate will be performed according to usual clinical practise

Detailed Description

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Conditions

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Graft Vs Host Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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no intervention

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients (children and adults) developing acute or chronic GvHD after HSCT.
* Age 6 months- month-99 years,
* Landsky-Karnofsky\> 70%,
* Acute or chronic GvHD needing further immunosuppressive treatment.
Minimum Eligible Age

6 Months

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna

OTHER

Sponsor Role lead

Responsible Party

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Prof. Franca Fagioli

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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AOU Città della Salute e della Scienza di Torino

Torino, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Franca Fagioli, MD

Role: CONTACT

+39011313 ext. 5997

Massimo Berger, MD

Role: CONTACT

+39011313 ext. 5997

Facility Contacts

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Celeste Cagnazzo, PhD

Role: primary

+39011313 ext. 5171

Other Identifiers

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GvHD damage on MSCs

Identifier Type: -

Identifier Source: org_study_id

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