Clinical Performance Evaluation of the NeuMoDx™ FluA/FluB/RSV/Severe Acute Respiratory Syndrome-CoV-2 Assay

NCT ID: NCT05162547

Last Updated: 2025-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2383 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-11

Study Completion Date

2024-02-07

Brief Summary

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To demonstrate the clinical performance of the NeuMoDx™ FluA/FluB/RSV/SARS-CoV-2 Assay on the NeuMoDx Systems by determining clinical sensitivity and specificity of the Assay.

Detailed Description

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To evaluate the clinical performance of the NeuMoDx™ FluA/FluB/RSV/SARS-CoV-2 Assay on the on the NeuMoDx™ 288 and 96 Molecular Systems, collectively referred to as NeuMoDx Systems. The results of this study will be used to support regulatory registration and product release in the US, Europe and other markets.

Conditions

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Respiratory Disease

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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NeuMoDx™ FluA/FluB/RSV/SARS-CoV-2 Assay

The NeuMoDx™ FluA/FluB/RSV/SARS-CoV-2 Assay (IUO) is a multiplexed, in vitro real-time Polymerase Chain Reaction assay, diagnostic test intended for the simultaneous qualitative detection and differentiation of Influenza A virus (Flu A), Influenza B virus (Flu B), Respiratory Syncytial Virus (RSV) and SARS-CoV-2 RNA

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Fresh specimens shall be collected from all comers across the study duration
* Collected from individuals of any age presenting with influenza-like illness (ILI)
* Nasopharyngeal (NP) swab specimen obtained using a flexible mini-tip flocked swab and collected into 3 mL Copan® Universal Transport Media (UTM) \[Cat. No.305c\] or Beckton Dickinson (BD™) Universal Viral Transport (UVT) \[Cat. No. 220531\]
* Minimum volume for residual specimen approximately 2 mL
* Fresh specimens to be tested within 3 days of collection.
* Fresh specimens to be stored under the recommended stability conditions (2-8°C).

Exclusion Criteria

* Required information unable to be obtained from associated medical chart.
* Specimens not fitting criteria outlined above.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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QIAGEN Gaithersburg, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sarah Johnson

Role: STUDY_DIRECTOR

QIAGEN Gaithersburg, Inc

Locations

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QIAGEN Gaithersburg, Inc

Manchester, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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SMF-21-2526-0-001

Identifier Type: -

Identifier Source: org_study_id

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