Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis
NCT ID: NCT05146180
Last Updated: 2026-01-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2022-02-24
2027-03-01
Brief Summary
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Detailed Description
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The definitive diagnosis according to the Duke-Li criteria will be established three months later in a multidisciplinary consultation meeting.
The final diagnosis according to the Duke-Li criteria will be made three months later in a multidisciplinary consultation meeting, blinded to the results of the parametric positron emission computed tomography, and with knowledge of the results of the standard positron emission computed tomography and the entire work-up.
Results and all the complementary work-up.
Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Parametric positron emission computed tomography
Parametric positron emission computed tomography
Patients will undergo parametric positron emission computed tomography in 15 days after the labeled polynuclear scintigraphy
Interventions
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Parametric positron emission computed tomography
Patients will undergo parametric positron emission computed tomography in 15 days after the labeled polynuclear scintigraphy
Eligibility Criteria
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Inclusion Criteria
* Effective contraception for women of childbearing age or negative pregnancy test on the day of the exam
* Good general condition. WHO ≤ 1
* Suspicion of endocarditis on a prosthetic heart valve implanted more than 3 months ago
* Labeled polynuclear scintigraphy performed within a maximum of 15 days before positron emission computed tomography
* Standard positron emission computed tomography planned as part of the extension assessment
* Informed and signed consent before any specific study procedure.
* Patient affiliated to the social security system
Exclusion Criteria
* Pregnancy or breastfeeding
* Poorly controlled diabetic patients
* Protected adults (under guardians or curators)
* Impossible decubitus (orthopnea, ...),
* Hypersensitivity to FDG or to one of the excipients of the radiopharmaceutical.
18 Years
ALL
No
Sponsors
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Centre Henri Becquerel
OTHER
Responsible Party
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Principal Investigators
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Mathieu Chastan, MD
Role: PRINCIPAL_INVESTIGATOR
Centre Henri Becquerel
Locations
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Centre Henri Becquerel
Rouen, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CHB18.10
Identifier Type: -
Identifier Source: org_study_id
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