Expanded Access Protocol for Subjects Previously Treated With Gedatolisib in B2151009

NCT ID: NCT05134922

Last Updated: 2025-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

AVAILABLE

Study Classification

EXPANDED_ACCESS

Brief Summary

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Continued access to treatment for subjects who continue benefit from therapy with gedatolisib in combination with palbociclib, and fulvestrant or letrozole.

Detailed Description

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The primary purpose of this study is to provide continuing access to treatment for subjects who continue benefit from therapy with gedatolisib in combination with palbociclib, and fulvestrant or letrozole.

Conditions

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Breast Neoplasm Malignant Female

Interventions

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Gedatolisib

Gedatolisib is a potent, reversible dual inhibitor that selectively targets phosphoinositide 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in biochemical and cellular assays.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Currently enrolled in the B2151009 clinical study and benefiting from treatment with gedatolisib in combination with other therapies as determined by the Investigator
2. Previously demonstrated compliance and are willing and able to comply with scheduled visits, treatment plans, and other study procedures
3. No evidence of progressive disease, as determined by the Investigator
4. Provide written informed consent prior to enrolling and receiving treatment

Exclusion Criteria

1. Permanently discontinued from treatment in Study B2151009, or discontinued from Study B2151009 for any reason
2. Women who are pregnant, intend to become pregnant, or nursing
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Celcuity Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Alabama at Birmingham

Birmingham, Alabama, United States

Site Status AVAILABLE

University of Michigan

Ann Arbor, Michigan, United States

Site Status AVAILABLE

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States

Site Status AVAILABLE

The University of Texas MD Anderson Cancer Center

Houston, Texas, United States

Site Status AVAILABLE

Seattle Cancer Care Alliance

Seattle, Washington, United States

Site Status AVAILABLE

Countries

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United States

Central Contacts

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Nadene Zack, MS

Role: CONTACT

844-310-3900

Facility Contacts

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Erica Stringer-Reasor, MD

Role: primary

Anne F Schott, MD

Role: primary

734-936-6266

Robert Weslowski, MD

Role: primary

Rachel Layman, MD

Role: primary

Jennifer Specht, MD

Role: primary

206-606-6768

Other Identifiers

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CELC-G-001

Identifier Type: -

Identifier Source: org_study_id

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