Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

NCT ID: NCT05094089

Last Updated: 2026-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

320 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-24

Study Completion Date

2030-07-31

Brief Summary

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The SYN 20-01 Study is a non-interventional, prospective, multicenter, multicohort, international, post-market clinical investigation looking into the assessment of GORE® SYNECOR Biomaterial in focused patient populations and in long-term application.

Patients with ventral / incisional hernia amenable to hernia mesh repair will be enrolled into two cohorts (US and EU cohort) and followed-up over the period of 60 months.

Detailed Description

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Conditions

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Hernia, Ventral Hernia Incisional Hernia Incisional Ventral

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SYNECOR IP Device

Hernia mesh repair with GORE® SYNECOR Intraperitoneal Biomaterial

Hernia repair with mesh

Intervention Type DEVICE

Hernia repair with GORE® SYNECOR Biomaterial; technical approach laparoscopic, robotic or open surgical / minimally invasive surgery

SYNECOR PRE Device

Hernia mesh repair with GORE® SYNECOR Preperitoneal Biomaterial

Hernia repair with mesh

Intervention Type DEVICE

Hernia repair with GORE® SYNECOR Biomaterial; technical approach laparoscopic, robotic or open surgical / minimally invasive surgery

Interventions

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Hernia repair with mesh

Hernia repair with GORE® SYNECOR Biomaterial; technical approach laparoscopic, robotic or open surgical / minimally invasive surgery

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* De-Novo ventral/incisional hernia amenable to repair with GORE® SYNECOR IP Biomaterial
* Clean wound (CDC Wound Class I)
* mVHWG Grade 1 or 2 (modified Ventral Hernia Working Group)


* De-novo ventral/incisional hernia, with subject anatomy and surgical plan amenable to open surgical repair or minimally invasive surgery with the GORE® SYNECOR PRE Biomaterial placed in a sublay fashion within the preperitoneal space
* Clean wound (CDC Wound Class I)
* mVHWG Grade 1 or 2 (modified Ventral Hernia Working Group)

Exclusion Criteria

\- Wound is either clean-contaminated, contaminated or dirty-infected


\- Wound is either clean-contaminated, contaminated or dirty-infected
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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W.L.Gore & Associates

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Emory Saint Joseph's Hospital

Atlanta, Georgia, United States

Site Status

Tufts Medical Center

Boston, Massachusetts, United States

Site Status

Corewell Health

Grand Rapids, Michigan, United States

Site Status

Lovelace Women's Hospital

Albuquerque, New Mexico, United States

Site Status

Stony Brook University Hospital

Stony Brook, New York, United States

Site Status

Novant Health New Hanover Regional Medical Center

Wilmington, North Carolina, United States

Site Status

Prisma Health Greenville Memorial Hospital

Greenville, South Carolina, United States

Site Status

Bon Secours Memorial Regional Medical Center

Mechanicsville, Virginia, United States

Site Status

Ospedale Civile di Baggiovara

Baggiovara, , Italy

Site Status

Vincenzo Monaldi Hospital

Napoli, , Italy

Site Status

Sapienza Università di Roma

Roma, , Italy

Site Status

University Hospital Virgen Macarena - Department of General And Digestive Surgery

Seville, , Spain

Site Status

Hospital Quirón Salud-Sagrado Corazón

Seville, , Spain

Site Status

University Hospitals Birmingham NHS Foundation Trust - Queen Elizabeth Hospital Birmingham

Birmingham, , United Kingdom

Site Status

Walsall Manor Hospital

Walsall, , United Kingdom

Site Status

Countries

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United States Italy Spain United Kingdom

Other Identifiers

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SYN 20-01

Identifier Type: -

Identifier Source: org_study_id

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