Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh

NCT ID: NCT04779918

Last Updated: 2025-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-29

Study Completion Date

2027-12-30

Brief Summary

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This study is designed to evaluate the post-operative complications and hernia recurrence following the use of OviTex in subjects with ventral or inguinal hernias. Up to 160 subjects will participate in the study from up to 20 investigator sites.

Detailed Description

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This study is intended to evaluate the post-operative complications and recurrence following the use of OviTex in ventral or inguinal hernias being treated robotically. It is a single-arm study and all subjects will receive OviTex.

Conditions

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Hernia, Ventral Hernia, Inguinal

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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OviTex Reinforced Tissue Matrix

This is a single-arm study. All study subjects will receive OviTex.

Group Type OTHER

OviTex Reinforced Tissue Matrix

Intervention Type DEVICE

All study subjects will receive OviTex. All OviTex Reinforced Tissue Matrices are intended for use as a surgical mesh to reinforce or repair soft tissue where weakness exists.

Interventions

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OviTex Reinforced Tissue Matrix

All study subjects will receive OviTex. All OviTex Reinforced Tissue Matrices are intended for use as a surgical mesh to reinforce or repair soft tissue where weakness exists.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject suffers from a ventral or inguinal hernia that requires surgical repair with the use of an implant to reinforce or replace weakened or missing tissue.
2. The patient is scheduled for an elective robotic approach with the use of OviTex LPR, OviTex Core Permanent, or OviTex 1S Permanent.
3. The size of the implant needed for repair is expected to be less than or equal to 15 x 25 cm for OviTex LPR and 25 x 40 cm for OviTex Core Permanent and OviTex 1S Permanent.
4. Subject meets CDC/SSI Wound Classification Class I (Clean), Class II (Clean-Contaminated) or Class III (Contaminated) criteria.
5. Subject is willing and able to sign an informed consent for the study and has signed the IRB approved Informed Consent form for this study.
6. Subject is able to complete Quality of Life (QoL) and pain questionnaires.
7. Subject is at least 21 years old.
8. Subject is willing to comply and able to participate fully in, and for the full duration of, the study including follow-up requirements.

Exclusion Criteria

1. Subject has a BMI of \> 40
2. Subject meets CDC/SSI Wound Classification Class IV (Dirty-Infected) criteria
3. Subject is female and is pregnant or plans to become pregnant during the course of the study.
4. Subject has a life expectancy of \< 2 years making it unlikely that the subject will successfully achieve two-year follow-up.
5. Subject has recent history of drug or alcohol abuse (in last 3 years).
6. Subject has an allergy to ovine-derived products.
7. Subject has participated in another clinical trial within the past 30 days or is currently involved in another clinical trial.
8. Subject has a strangulated hernia.


1. Subject requires implant that cannot be introduced into the surgical site during the procedure via port or an existing incision.
2. Subject unable to receive OviTex LPR, OviTex Core Permanent, or OviTex 1S Permanent time of surgery.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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MCRA

INDUSTRY

Sponsor Role collaborator

Tela Bio Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Geoffrey Slayden, MD

Role: PRINCIPAL_INVESTIGATOR

St. Lukes Hospital

Locations

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University of South Alabama

Mobile, Alabama, United States

Site Status RECRUITING

SurgOne

Denver, Colorado, United States

Site Status ACTIVE_NOT_RECRUITING

GenesisCare

Destin, Florida, United States

Site Status TERMINATED

Surgical Healing Arts Center

Fort Myers, Florida, United States

Site Status TERMINATED

St. Luke's Hospital

Overland Park, Kansas, United States

Site Status RECRUITING

University of Louisville

Louisville, Kentucky, United States

Site Status RECRUITING

Munson Healthcare

Traverse City, Michigan, United States

Site Status RECRUITING

St. Francis Hospital

Roslyn, New York, United States

Site Status WITHDRAWN

Mohawk Valley Health System

Utica, New York, United States

Site Status RECRUITING

Houston Methodist

Houston, Texas, United States

Site Status ACTIVE_NOT_RECRUITING

Countries

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United States

Central Contacts

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Melissa LaMantia

Role: CONTACT

757-761-4922

Danielle Campbell

Role: CONTACT

717-676-2589

Facility Contacts

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Valrie Patterson, RN

Role: primary

251-445-9626

Patti Wyman

Role: primary

Dajana Nenadovic, RN

Role: primary

502-588-4571

Kelly VanSchouwen

Role: primary

Kristen Crowder, RN

Role: primary

315-624-4831

Other Identifiers

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TB.2020.01.01

Identifier Type: -

Identifier Source: org_study_id

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