Examining a Training Program for for Acute Lymphoblastic Leukemia Childhood Cancer Survivors

NCT ID: NCT05086354

Last Updated: 2022-02-11

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 10 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-03-16
• Study Completion Date: 2021-12-31

Brief Summary

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, with the peak incidences occurring in children two to five years of age. Children with ALL received neurotoxic chemotherapy agents for two to three years that causes decreased distal muscle strength and poor timing of muscle activation. After completion of medical treatment, ALL childhood cancer survivors (ALL CCS) are more likely to have an inactive lifestyle, resulting in life-long gross motor proficiency differences compared to their peers. ALL CCS typically do not utilize physical therapists' expertise after medical treatment has been completed. There are limited physical therapy (PT) intervention studies for ALL CCS.

Detailed Description

We are performing a feasibility study to examine a movement based intervention that utilizes fast movements through jumping rope to improve balance, coordination, movement speed, and movement agility. The abilities to generate fast movements are required to perform functional activities and for playing sports. Participants will receive five in-person PT sessions and a home program for six weeks. The goal of this research is to determine the feasibility, acceptability, and promise of a PT program that emphasizes fast movements in ALL CCS.

Conditions

Childhood Cancer

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

One group that all receive the intervention of jumping rope.

All participants will be in one group. Every participant receives the same intervention.

Group Type: EXPERIMENTAL

JUMP

Intervention Type: BEHAVIORAL

Warm-up, stretching, jumping rope, cool-down

Interventions

JUMP

Warm-up, stretching, jumping rope, cool-down

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Children 6-17 years old
• Completed medical treatment for ALL within the past five years (1 to 60 months)
• Speak English.

Exclusion Criteria

• Diagnosis of a neurological disorder such as cerebral palsy, Down syndrome
• Currently receiving PT services.

• Minimum Eligible Age: 6 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Maryland, Baltimore

OTHER

Sponsor Role: lead

Responsible Party

victoria marchese

Associate Professor, Chair

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Victoria Marchese, PT, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Maryland, Baltimore

Locations

University of Maryland School of Medicine Dept. of Physical Therapy & Rehabilitation Science

Baltimore, Maryland, United States

Countries

United States

Other Identifiers

HP-00078339

Identifier Type: -

Identifier Source: org_study_id