ASPIRES (Activating Cancer Survivors and Their Primary Care Providers to Increase Colorectal Cancer Screening) Study
NCT ID: NCT05084833
Last Updated: 2025-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
300 participants
INTERVENTIONAL
2022-02-14
2025-09-30
Brief Summary
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Detailed Description
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The primary outcome is the proportion of patients who complete the colonoscopy or Cologuard test (Cologuard test plus colonoscopy if the Cologuard is positive) within 12 months of enrolling on the study, as measured via self-report questions in the end of study questionnaire. The study will test the hypothesis that, compared to controls, survivors randomized to the PA and PA + PCP activation groups will have significantly higher rates of completion of colorectal cancer screening.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Group1: Control (C)
Electronic educational materials (C).
Control
Electronic educational materials
Group 2: Patient Activation (PA)
C + patient activation (PA) consisting of interactive tailored text messages with links to videos and resources
Patient activation
Interactive text messages with links to videos (e.g. colorectal cancer screening options, cost of colorectal cancer screening, perspective from a cancer survivor, why regular appointments are important for cancer survivors) and resources (e.g. helpful websites) are sent to participants
Control
Electronic educational materials
Group 3: Patient Activation and PCP Activation (PA + PCP)
C + PA + PCP activation (PA+PCP) with physician materials about colorectal cancer risk in this population
Patient activation
Interactive text messages with links to videos (e.g. colorectal cancer screening options, cost of colorectal cancer screening, perspective from a cancer survivor, why regular appointments are important for cancer survivors) and resources (e.g. helpful websites) are sent to participants
Primary care provider activation
Faxed educational materials (e.g. current colorectal cancer screening recommendations, frequently asked questions, insurance letter template, cover letter with overview of patient's cancer treatment history) sent to primary care providers
Control
Electronic educational materials
Interventions
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Patient activation
Interactive text messages with links to videos (e.g. colorectal cancer screening options, cost of colorectal cancer screening, perspective from a cancer survivor, why regular appointments are important for cancer survivors) and resources (e.g. helpful websites) are sent to participants
Primary care provider activation
Faxed educational materials (e.g. current colorectal cancer screening recommendations, frequently asked questions, insurance letter template, cover letter with overview of patient's cancer treatment history) sent to primary care providers
Control
Electronic educational materials
Eligibility Criteria
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Inclusion Criteria
* Enrolled on the Childhood Cancer Survivor Study
* Were treated with radiation to the abdomen, pelvis, spine, or total body irradiation
* Have no history of colorectal cancer
* Have not had a colonoscopy in the last 5 years or Cologuard in the last 3 years
* Have a smartphone
Exclusion Criteria
* Do not speak English
30 Years
ALL
No
Sponsors
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The Hospital for Sick Children
OTHER
Duke University
OTHER
Penn State University
OTHER
St. Jude Children's Research Hospital
OTHER
Memorial Sloan Kettering Cancer Center
OTHER
Columbia University
OTHER
Hunter College of City University of New York
OTHER
National Cancer Institute (NCI)
NIH
Ann & Robert H Lurie Children's Hospital of Chicago
OTHER
Responsible Party
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Principal Investigators
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Tara O Henderson, MD, MPH
Role: PRINCIPAL_INVESTIGATOR
Ann & Robert H Lurie Children's Hospital of Chicago
Karen Kim, MD, MS
Role: STUDY_CHAIR
The Pennsylvania State University
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, United States
Columbia University
New York, New York, United States
The Pennsylvania State University
University Park, Pennsylvania, United States
St. Jude Children's Research Hospital
Memphis, Tennessee, United States
Countries
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References
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Henderson TO, Bardwell JK, Moskowitz CS, McDonald A, Vukadinovich C, Lam H, Curry M, Oeffinger KC, Ford JS, Elkin EB, Nathan PC, Armstrong GT, Kim K. Implementing a mHealth intervention to increase colorectal cancer screening among high-risk cancer survivors treated with radiotherapy in the Childhood Cancer Survivor Study (CCSS). BMC Health Serv Res. 2022 May 23;22(1):691. doi: 10.1186/s12913-022-08082-3.
Other Identifiers
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STUDY00000296
Identifier Type: -
Identifier Source: org_study_id
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