Transcriptomic Study of IBD-associated Colorectal Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2021-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Chronic inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer (CRC) in historical cohorts. The pathways of oncogenesis of these CRCs, which are very different clinically from de novo CRCs, are currently unknown. The aim of our work is to identify specific molecular signatures of CRC occurring in the setting of IBD.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease

NCT02726243

Inflammatory Bowel Disease Colorectal Cancer

COMPLETED

Risk Factors for Colorectal Cancer in Patients With Inflammatory Bowel Disease Undergoing Surveillance: a Prospective Cohort Study

NCT01464151

Inflammatory Bowel Disease Colorectal Cancer

COMPLETED

Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC

NCT05530746

Colorectal Cancer Precancerous Lesion Inflammatory Bowel Diseases

UNKNOWN

Usefulness of Chromoendoscopy for the Early Detection of Colorectal Cancer Associated With Inflammatory Bowel Disease

NCT02543762

Inflammatory Bowel Disease Colorectal Cancer

COMPLETED

The Role of Gut Microbiome and Chronic Inflammation in Young-onset Colorectal Cancer

NCT04011969

Colorectal Cancer

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Colorectal Cancer, Genetics of

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

transcriptomic analysis

transcriptomic analysis on preserved tumor tissue

Intervention Type GENETIC

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Person 18 years of age or older
* Person with colorectal cancer in the context of IBD
* Person who has received complete information on the organization of the research and who has signed an informed consent
* Person affiliated to a social security plan or beneficiary of such a plan.

Exclusion Criteria

* Person referred to in articles L. 1121-5, L. 1121-7 and L1121-8 of the public health code:
* Pregnant woman, parturient or nursing mother
* Minor (not emancipated)
* Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
* Person of legal age who is unable to express his or her consent
* Person deprived of liberty by a judicial or administrative decision, persons subject to psychiatric care under articles L. 3212-1 and L. 3213-1.

Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No