Examination of a New Irrigation System for Transanal Irrigation in Children With Fecal Incontinence

NCT ID: NCT05032534

Last Updated: 2022-08-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-20

Study Completion Date

2022-07-31

Brief Summary

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The aim of this study is to investigate if a new irrigation system for transanal irrigation (TAI) is effective and more tolerable than the currently used system at the Pediatric Ward at Aarhus University Hospital.

Detailed Description

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This is a randomized, controlled study.

This study will be performed at Aarhus University Hospital (Denmark) and Aalborg University Hospital (Denmark) following the same protocol.

According to the initial randomization, children will be allocated to treatment with the new system (group A) or with the currently used system (group B). After a period of 6 weeks the child will crossover to use the contrary system.

The hypothesis is that A TAI system specifically developed for children will enhance the child's toleration of irrigation due to fewer reports on pain at insertion which will lead to better compliance. This outcome will induce a comparable or better effect on their fecal incontinence and reduce the needed follow-up period due to fewer incontinence relapse.

Conditions

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Fecal Incontinence Constipation - Functional

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

The children will use either the old or the new cone for transanal irrigation for 6 weeks and then crossover to the contrary cone.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Newly developed cone for 6 weeks the currently used cone for 6 weeks

Starts off with treatment with the newly developed cone for transanal irrigation for 6 weeks and are then instructed to crossover to the contrary system, the currently used, for additional 6 weeks.

Group Type ACTIVE_COMPARATOR

Cone Small, Qufora A/S

Intervention Type DEVICE

Newly developed cone in a softer material and a design matching the use for transanal irrigation.

Colotip, Coloplast A/S

Intervention Type DEVICE

Cone currently used for transanal irrigation at the Pediatric Ward, Aarhus University Hospital.

Currently used cone for 6 weeks the newly developed cone for 6 weeks

Starts off with treatment with the currently used cone for transanal irrigation for 6 weeks and are then instructed to crossover to the contrary system, the currently used, for additional 6 weeks.

Group Type ACTIVE_COMPARATOR

Cone Small, Qufora A/S

Intervention Type DEVICE

Newly developed cone in a softer material and a design matching the use for transanal irrigation.

Colotip, Coloplast A/S

Intervention Type DEVICE

Cone currently used for transanal irrigation at the Pediatric Ward, Aarhus University Hospital.

Interventions

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Cone Small, Qufora A/S

Newly developed cone in a softer material and a design matching the use for transanal irrigation.

Intervention Type DEVICE

Colotip, Coloplast A/S

Cone currently used for transanal irrigation at the Pediatric Ward, Aarhus University Hospital.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Fecal incontinence on neurogenic or non-neurogenic basis, where transanal irrigation is indicated.

Exclusion Criteria

* Morbus Hirschsprungs disease.
* Anorectal malformations.
* Use of medication that are known to cause constipation (e.g. anticholinergics)
Minimum Eligible Age

5 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aarhus University Hospital

OTHER

Sponsor Role collaborator

Aalborg University Hospital

OTHER

Sponsor Role collaborator

Qufora A/S

INDUSTRY

Sponsor Role collaborator

University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Aarhus University Hospital

Aarhus, Central Jutland, Denmark

Site Status

Aalborg University Hospital

Aalborg, The North Denmark Region, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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Højt skyl

Identifier Type: -

Identifier Source: org_study_id

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