Perceived Barriers to Patient Adherence After Pediatric Solid Organ Transplantation
NCT ID: NCT01370746
Last Updated: 2017-06-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
502 participants
OBSERVATIONAL
2012-04-30
2014-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Cross-Sectional Study Group
Cross-sectional comparison of perceived barriers to adherence to post-transplant immunosuppressant regimens in parents/legal guardians of children 0-11 years versus adolescents 12-21 years
No interventions assigned to this group
Longitudinal Study Group
Subset of Cross-Sectional Study Group to evaluate whether perceived barriers to adherence increase with time during the first year following transplantation
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Male or female primary solid organ transplant patients 0-21 years of age
* Recipients at least 1 month post-transplant hospital discharge
Exclusion Criteria
* Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete the questionnaires
* Re-transplant recipient
* Multi-organ transplant recipient
21 Years
ALL
No
Sponsors
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Clinical Trials in Organ Transplantation in Children
OTHER
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Responsible Party
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Principal Investigators
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Stuart Sweet, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Washington University School of Medicine
Lara Danziger-Isakov, MD, MPH
Role: STUDY_CHAIR
Children's Hospital Medical Center, Cincinnati
Locations
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University of Alabama
Birmingham, Alabama, United States
Ronald Reagan UCLA Medical Center (Mattel Childrens')
Los Angeles, California, United States
University of California San Francisco Children's Hospital
San Francisco, California, United States
Lucile Packard Children's Hospital at Stanford
Stanford, California, United States
University of Florida Health Sciences Center
Gainesville, Florida, United States
Emory Children's Center
Atlanta, Georgia, United States
Children's Hospital of Boston
Boston, Massachusetts, United States
Washington University School of Medicine
St Louis, Missouri, United States
Children's Hospital of New York
New York, New York, United States
The Cleveland Clinic
Cleveland, Ohio, United States
Nationwide Children's Hospital
Columbus, Ohio, United States
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania, United States
Baylor College of Medicine/Texas Children's Hospital
Houston, Texas, United States
Children's Hospital and Regional Medical Center
Seattle, Washington, United States
Countries
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References
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Shemesh E. Barriers to adherence - To screen or not to screen, that is the question. Pediatr Transplant. 2016 Mar;20(2):188-90. doi: 10.1111/petr.12671. Epub 2016 Jan 22. No abstract available.
Danziger-Isakov L, Frazier TW, Worley S, Williams N, Shellmer D, Dharnidharka VR, Gupta NA, Ikle D, Sweet SC; CTOTC-05 Consortium. Perceived barriers to medication adherence in pediatric and adolescent solid organ transplantation. Pediatr Transplant. 2016 Mar;20(2):307-15. doi: 10.1111/petr.12648. Epub 2015 Dec 16.
Related Links
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National Institute of Allergy and Infectious Diseases (NIAID)
Division of Allergy, Immunology, and Transplantation (DAIT)
Clinical Trials in Organ Transplantation in Children (CTOT-C)
Other Identifiers
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DAIT CTOTC-05
Identifier Type: -
Identifier Source: org_study_id
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