Spectrum of Bacterial Infections in Rheumatology

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

81 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-12

Study Completion Date

2021-12-31

Brief Summary

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Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are :

* To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome
* To compare OAI of urinary origin with those with another origin

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Detailed Description

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This retrospective study will be conducted on medical files. Patients will be mainly selected on :

* A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020.
* Adult patients 18 year's old or older
* Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features)

The followed OAI are not included :

* Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis
* Brucellosis ; Lyme disease

Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators.

OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy.

* Characteristics of three populations will be compared :
* \- OAI of urinary origin
* \- OAI of another origin (skin, etc)
* \- OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.

Conditions

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Articular Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Osteoarticular infections

Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Groups/Cohortes

Intervention Type OTHER

Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Interventions

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Groups/Cohortes

Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Intervention Type OTHER

Other Intervention Names

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Osteoarticular infections

Eligibility Criteria

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Inclusion Criteria

* Subject aged 18 years and over at the time of diagnosis
* Osteoarticular infection (septic arthritis, spondylodiscitis), by a bacterium or a fungus, proven by a bacteriological sample in situ or in the blood by positive blood culture (with an unequivocal clinical, biological and imaging feature),
* Diagnosed between 01/01/2010 and 12/31/2020 (11 years)
* Hospitalization in the rheumatology department of CH René Dubos, Pontoise

Exclusion Criteria

* Bacterial infection due to the following germs: mycobacteria, brucella, Borrelia
* Early infection on joint prosthesis
* Peripheral osteomyelitis
* Osteoarticular infection without bacteriological proof

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No