Wearable Vibration Effect on Biomechanics and Biomarkers After ACL Reconstruction

NCT ID: NCT05001594

Last Updated: 2024-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-30

Study Completion Date

2023-10-07

Brief Summary

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Anterior cruciate ligament (ACL) injuries account for up to 25% of knee injuries, it is estimated that 32,000-400,000 new cases of ACL tears occur in the USA every year.

The Standard care is twofold; a) ACL reconstruction surgery and b) prolonged rehabilitation period (usually no less than 9 months). However, a large amount of patients do not return to their pre-injury activity level, and up to 30% reinjure their ACL in the following two years.

The wearable system consists of two non-invasive bands, above and below the knee that vibrate during the weight bearing phase while walking.

Detailed Description

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The objective of this study is to investigate the effect of treatment for ACL reconstruction, including vibrational stimulation and pressure, on locomotion tasks (i.e. walking, stair ascending and descending), muscle function, and pain/function.

Conditions

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Anterior Cruciate Ligament Injuries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Usual care+ Sham device

Each participant will go through the normal rehabilitation process that follows ACL reconstruction+ a sham device used in the same was as the intervention group.

The sham device will look the same, will gave the same pressure around the leg, but will not vibrate.

Group Type NO_INTERVENTION

No interventions assigned to this group

Usual care+ knee vibratory device

Each participant will go through the normal rehabilitation process that follows ACL reconstruction. Additionally, each participant will receive the active device that applies non-invasive vibrational stimulation to the leg for two months, and will be asked to wear it during ambulation for at least an hour per day.

Group Type EXPERIMENTAL

Active vibratory knee device

Intervention Type DEVICE

The active, wearable device is placed above and below the knee joint. The device consists of a sensing module to determine specific points in the gait cycle, a processor to analyze signal from the sensor, and a stimulus module to provide vibratory feedback to the subject.

Normative data

Healthy participants will go through one session of the full protocol (excluding blood tests):

* Questionnaires (IKDC, TSK, GAD-7).
* Biomechanical analysis during walking, stair ambulation, and hoping.
* Quadriceps and Hamstring strength testing

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Active vibratory knee device

The active, wearable device is placed above and below the knee joint. The device consists of a sensing module to determine specific points in the gait cycle, a processor to analyze signal from the sensor, and a stimulus module to provide vibratory feedback to the subject.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Provision of signed and dated informed consent form
* Males and females
* Aged 18-50
* Scheduled for an ACL reconstruction in Rambam hospital.
* Hebrew language at mother tongue level

Exclusion Criteria

* Inability to understand the study protocol.
* Known neuropathies, active cancer, previous fractures in the lower limbs, inflammatory arthritis, implanted electronic devices of any kind.
* Allergies to silver or adhesives.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role collaborator

Technion, Israel Institute of Technology

OTHER

Sponsor Role lead

Responsible Party

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Arielle Fischer

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Arielle Fischer, PhD

Role: PRINCIPAL_INVESTIGATOR

Technion, Israel Institute of Technology

Bezalel Peskin, MD

Role: PRINCIPAL_INVESTIGATOR

Rambam Health Care Campus

Locations

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Rambam Health Care Campus

Haifa, , Israel

Site Status

Countries

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Israel

Other Identifiers

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0089-21-RMB

Identifier Type: -

Identifier Source: org_study_id

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