Multi-omics Research of Idopathic Normal Pressure Hydrocephalus (iNPH)
NCT ID: NCT04998175
Last Updated: 2021-08-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2020-09-15
2022-12-30
Brief Summary
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Detailed Description
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Methods- The primary methods used are:
1. The cerebrospinal fluid proteomic analysis of iNPH patients before and after VP shunt surgery.
2. The structral and functional MRI analysis of iNPH patients
3. The clinical assessment of MMSE, gait scores, Kiefer score, and mRS. Objective- To study the prognostic factors of VP shunt for iNPH.
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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iNPH cohort
The patients diagnosed of iNPH.
ventriculo-peritoneal shunt
A ventriculoperitoneal shunt is a tube that drains excess cerebrospinal fluid into abdomen
Interventions
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ventriculo-peritoneal shunt
A ventriculoperitoneal shunt is a tube that drains excess cerebrospinal fluid into abdomen
Eligibility Criteria
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Inclusion Criteria
* Diagnosis of iNPH based on clinical assessment
* Participant is able to give written informed consent
Exclusion Criteria
* Participant is not medically available for shunt surgery
* Secondary NPH
60 Years
90 Years
ALL
No
Sponsors
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Westlake University
OTHER
Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Principal Investigators
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Zhoule Zhu
Role: PRINCIPAL_INVESTIGATOR
Second Affiliated Hospital, School of Medicine, Zhejiang University
Locations
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The second affliated hospital of zhejiang university
Hangzhou, Zhejiang, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2020-796
Identifier Type: -
Identifier Source: org_study_id
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