Project FLUx COntact-CoVID-19 Faculty of Medicine Paris-Saclay

NCT ID: NCT04991246

Last Updated: 2023-02-06

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 210 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-10-14
• Study Completion Date: 2022-01-14

Brief Summary

The worldwide health system has been marked by the SARS-CoV-2 pandemic. French educational system has been upset, especially medical schools, which, because of their hospital location, are particularly exposed to the spread of the virus. The medical school of Paris-Saclay University, located within bicetre University Hospital, AP-HP, must therefore adapt on a daily basis to ensure educational continuity. Taking advantage of an exceptional scientific ecosystem, innovative viral epidemic propagation modeling approaches based on both simulation and contact tracing data will be tested in real-life conditions. These propagation models will serve to scientifically optimize future educational organization procedures in this medical school.

Detailed Description

All the participants will be equipped with individual wireless contact tracing technology. Anonymised contact events will be automatically monitored for a period of two months to measure the daily contact flow density between the students at medical school. Epidemic simulation models will be enriched with these real contact tracing data to generate optimized viral propagation probability networks. During the same period, CO2 measurement will be performed in several relevant sectors (classrooms, amphitheaters, corridors etc) to allow a more holistic understanding of the propagation conditions. Finally, the probabilistic models will be confronted to the results of a two step COVID-19 screening campaign.

Conditions

Covid19

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: NONE

Study Groups

Students, teachers,administrative staff from the medical school of Paris-Saclay University

Students,teachers,administrative staff from the medical school of Paris-Saclay University

Group Type: EXPERIMENTAL

Antigenic tests (on saliva samples)

Intervention Type: OTHER

SARS-CoV-2 screening tests: two massive antigenic tests campaigns (on salivary samples).

Individual electronic sensor port

Intervention Type: OTHER

Individual electronic sensor recording contacts but not their location (in the form of a bracelet, a key ring or a badge) Contact data collection points (5 maximum, located at compulsory passage points for participants). When a sensor is close to one of these terminals, it discharges its contacts in seconds.

Atmospheric measurements of CO2

Intervention Type: OTHER

Atmospheric measurements of CO2 in the relevant closed places of the faculty (lectures / practical work / BU / refectory): battery operated sensors. When a sensor is installed in a place, the ventilation conditions (number of open windows, etc.) as well as the number of people present will be noted.

Interventions

Antigenic tests (on saliva samples)

SARS-CoV-2 screening tests: two massive antigenic tests campaigns (on salivary samples).

Intervention Type: OTHER

Individual electronic sensor port

Individual electronic sensor recording contacts but not their location (in the form of a bracelet, a key ring or a badge) Contact data collection points (5 maximum, located at compulsory passage points for participants). When a sensor is close to one of these terminals, it discharges its contacts in seconds.

Intervention Type: OTHER

Atmospheric measurements of CO2

Atmospheric measurements of CO2 in the relevant closed places of the faculty (lectures / practical work / BU / refectory): battery operated sensors. When a sensor is installed in a place, the ventilation conditions (number of open windows, etc.) as well as the number of people present will be noted.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Volunteers of adult men and women over 18 from the Paris-Saclay Medicine UFR

• Belonging to the teaching staff
• Belonging to the promotions of DFGSM 2 and 3, and DFASM 1 and 2 (2nd to 5th year of medical study)
• administrative staff
• Affiliated to a social security scheme or beneficiary (excluding AME)
• Informed and written consent

Exclusion Criteria

• Absence of intercurrent disease before inclusion
• Positive antigenic or PCR test at the time of inclusion

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 100 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Olivier LAMBOTTE, Pr

Role: PRINCIPAL_INVESTIGATOR

Bicetre Hospital

Locations

CHU Bicêtre

Le Kremlin-Bicêtre, , France

Countries

France

Other Identifiers

2021-A00663-38

Identifier Type: OTHER

Identifier Source: secondary_id

APHP210403

Identifier Type: -

Identifier Source: org_study_id