Blood Coagulation Abnormalities in COVID-19 (Corona Virus Disease-19) Patients

NCT ID: NCT04982263

Last Updated: 2021-07-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

125 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2021-05-31

Brief Summary

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The role of the coagulation parameters in predicting the severity of COVID-19 disease will be assessed

Detailed Description

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In COVID-19 patients the coagulation parameters Prothrombin concentration (PC), Activated Partial Thromboplastin Time (aPTT), D Dimer, Antithrombin III (ATIII) and Fibrinogen are measured and correlation with disease severity is to be investigated

Conditions

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Covid19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Mild cases

Patients with confirmed COVID-19 and with mild disease

Blood coagulation profile

Intervention Type DIAGNOSTIC_TEST

Venous blood sample for measurement of blood coagulation profile

Severe cases

Patients with confirmed COVID-19 and with severe disease

Blood coagulation profile

Intervention Type DIAGNOSTIC_TEST

Venous blood sample for measurement of blood coagulation profile

Interventions

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Blood coagulation profile

Venous blood sample for measurement of blood coagulation profile

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

● Confirmed cases with COVID 19

Exclusion Criteria

● Known history of blood coagulopathy disorder
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Hend Mohammed Abdelraheem Esmaeel

assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hend mohamed A Esmaeel, M.D

Role: PRINCIPAL_INVESTIGATOR

Sohag Univesity

Locations

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Sohag University

Sohag, , Egypt

Site Status

Sohag University

Sohag, , Egypt

Site Status

Countries

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Egypt

References

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Fauci AS, Lane HC, Redfield RR. Covid-19 - Navigating the Uncharted. N Engl J Med. 2020 Mar 26;382(13):1268-1269. doi: 10.1056/NEJMe2002387. Epub 2020 Feb 28. No abstract available.

Reference Type BACKGROUND
PMID: 32109011 (View on PubMed)

Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020 Apr;18(4):844-847. doi: 10.1111/jth.14768. Epub 2020 Mar 13.

Reference Type BACKGROUND
PMID: 32073213 (View on PubMed)

Terpos E, Ntanasis-Stathopoulos I, Elalamy I, Kastritis E, Sergentanis TN, Politou M, Psaltopoulou T, Gerotziafas G, Dimopoulos MA. Hematological findings and complications of COVID-19. Am J Hematol. 2020 Jul;95(7):834-847. doi: 10.1002/ajh.25829. Epub 2020 May 23.

Reference Type BACKGROUND
PMID: 32282949 (View on PubMed)

Other Identifiers

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Soh-Med-21-07-34

Identifier Type: -

Identifier Source: org_study_id

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