Effect of a Probiotic Strain Lactobacillus Paracasei K56 on Metabolic Symptom - a Pilot Study
NCT ID: NCT04980599
Last Updated: 2023-01-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
118 participants
INTERVENTIONAL
2021-01-10
2021-12-31
Brief Summary
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In this before-after pilot study, the participants were randomly assigned to 8 groups to compare the fat-reducing effect of the Lactobacillus paracasei K56 by continuously supplementing different product prototypes , and screen the best probiotic K56 prototype with the effect of fat reduction.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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K56 very high dose -E1
Probiotic drink (lactobacillus paracasei K56 10\^11CFU) 350ml/d , for 60days
probiotic drink with Lactobacillus paracasei K56
Probiotic drink (K56 10\^11CFU) 350ml/d for 60days
control -E2
maltodextrin , for 60days
maltodextrin
maltodextrin ,for 60days
K56 high dose-E3
Probiotic powder 1.5g/sachet , 3.0g/d (lactobacillus paracasei K56 10\^10cfu) , for 60days
Probiotic powder E3
Probiotic powder 3.0g/d (K56 10\^10cfu) 60days;
K56 middle dose-E5
Probiotic powder 8.0g/sachet , 8g/d ( Lactobacillus paracasei K56 10\^9cfu) , for 60days
Probiotic powder E5
probiotic powder 8g/day for 60days
K56 low dose -E7
probiotic k56 capsule, 2capsules/d ( Lactobacillus paracasei K56 10\^7cfu) , for 60days
probiotic capsule E7
probiotic k56 capsule, 2capsules/d (10\^7cfu) for 60days
K56 middle dose-E9
probiotic K56 capsule, 2capsules/d (Lactobacillus paracasei K56 10\^9cfu) ,for 60days
probiotic capsule E9
probiotic k56 capsule, 2capsules/d (10\^9cfu) for 60days
K56 high dose-E1K
probiotic K56 capsule, 2capsules/d (Lactobacillus paracasei K56 10\^10cfu), for 60days
probiotic capsule E10
probiotic k56 capsule, 2capsules/d (10\^10cfu) for 60days
K56 very high dose-E11
probiotic K56 capsule, 4capsules/d (Lactobacillus paracasei K56 10\^11cfu) ,for 60days
probiotic capsule E11
probiotic k56 capsule, 4capsules/d (10\^11cfu) for 60days
Interventions
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probiotic drink with Lactobacillus paracasei K56
Probiotic drink (K56 10\^11CFU) 350ml/d for 60days
maltodextrin
maltodextrin ,for 60days
Probiotic powder E3
Probiotic powder 3.0g/d (K56 10\^10cfu) 60days;
Probiotic powder E5
probiotic powder 8g/day for 60days
probiotic capsule E7
probiotic k56 capsule, 2capsules/d (10\^7cfu) for 60days
probiotic capsule E9
probiotic k56 capsule, 2capsules/d (10\^9cfu) for 60days
probiotic capsule E10
probiotic k56 capsule, 2capsules/d (10\^10cfu) for 60days
probiotic capsule E11
probiotic k56 capsule, 4capsules/d (10\^11cfu) for 60days
Eligibility Criteria
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Inclusion Criteria
* Age: 18 - 60 years old adults
Exclusion Criteria
* History of intervention with fat-reducing drugs or health products in the past 2 months
* take weight control measures (diet, exercise, etc.) within the past month
* Those who cannot guarantee to maintain their current lifestyle during the trial period
* Those who fail to consume the tested samples as required, or fail to follow up on time, resulting in failure to determine the efficacy
18 Years
60 Years
ALL
Yes
Sponsors
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Inner Mongolia Yili Industrial Group Co., Ltd
INDUSTRY
Fudan University
OTHER
Responsible Party
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Zhijun Bao
Director
Principal Investigators
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Ying Feng, Ph.D
Role: STUDY_DIRECTOR
Hua Dong Hospita Affiliated to Fu Dan University, Shanghai,China
Locations
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Hua Dong Hospital Affiliated to Fu Dan University
Shanghai, , China
Countries
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References
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Kadeer G, Fu W, He Y, Feng Y, Liu WH, Hung WL, Feng H, Zhao W. Effect of different doses of Lacticaseibacillus paracasei K56 on body fat and metabolic parameters in adult individuals with obesity: a pilot study. Nutr Metab (Lond). 2023 Mar 21;20(1):16. doi: 10.1186/s12986-023-00739-y.
Other Identifiers
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ZBao
Identifier Type: -
Identifier Source: org_study_id
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