Nephrogenic Diabetes Insipidus During Prolonged Sevoflurane Sedation in the ICU: a Retrospective Analysis

NCT ID: NCT04939753

Last Updated: 2023-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-05-26

Study Completion Date

2023-04-01

Brief Summary

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The investigators aim to retrospectively explore the electronic medical records of all patients who were admitted to the Intensive Care Unit (ICU) of the UZ Brussels in the last 10 years (March 1st 2011- March 1st 2021) and who received prolonged sedation (\>24h) with sevoflurane.

Detailed Description

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Conditions

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Nephrogenic Diabetes Insipidus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Sevoflurane group

Patients that received sevoflurane while in ICU care.

Sevoflurane

Intervention Type DRUG

Sevoflurane administration to sedate the patient

Interventions

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Sevoflurane

Sevoflurane administration to sedate the patient

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Sevoflurane administration \>24h
* 18 years and older

Exclusion Criteria

* \< 18 years old
* Pre-existing diabetes insipidus
* Use of drugs at risk for diabetes insipidus (including lithium, cisplatin)
* Hypercalcemia (persistently \>2.75 mmol/L)
* Pituitary or acute brain surgery
* Patients requiring continuous renal replacement therapy
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitair Ziekenhuis Brussel

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UZ Brussel

Jette, Brussels Capital, Belgium

Site Status

Countries

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Belgium

Other Identifiers

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Sevoflu-DI-IZ

Identifier Type: -

Identifier Source: org_study_id

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