Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

NCT ID: NCT04929574

Last Updated: 2021-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-01

Study Completion Date

2025-12-30

Brief Summary

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Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.

Detailed Description

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Conditions

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Beta Thalassemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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beta thalassemia patients

Echocardiogram and Hematological Analysis

Intervention Type DIAGNOSTIC_TEST

Echocardiogram and Hematological Analysis

Interventions

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Echocardiogram and Hematological Analysis

Echocardiogram and Hematological Analysis

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with beta-thalassemia

Exclusion Criteria

* Iron deficiency anemia
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ZhuHai Hospital

OTHER

Sponsor Role collaborator

Shenzhen Children's Hospital

OTHER_GOV

Sponsor Role collaborator

Shenzhen Second People's Hospital

OTHER

Sponsor Role collaborator

Jiangmen Maternity and Child Health Care Hospital

UNKNOWN

Sponsor Role collaborator

Yongzhou Maternity and Child Health Hospital

UNKNOWN

Sponsor Role collaborator

Nanfang Hospital, Southern Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Southern Medical University

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Xiangmin Xu, Prof. Dr.

Role: CONTACT

(20) 61648293 ext. 86

Facility Contacts

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Xiangmin Xu, Prof. Dr.

Role: primary

(20) 61648293 ext. 86

Other Identifiers

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Heart-Beta thalassemia

Identifier Type: -

Identifier Source: org_study_id

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