Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
20 participants
OBSERVATIONAL
2020-06-01
2022-12-30
Brief Summary
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Detailed Description
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Cells are the basic unit of brain. Understanding the mechanism of brain activities includes not only the mechanism of neural network, but also the self-regulation of its basic unit, that is, the regulation of gene expression based on brain activity.The abnormal expression and regulation of genes lead to the abnormal activities of the nervous system.Therefore, studying the regulation mechanism of gene expression at the cellular level is an important way to research brain diseases.The recent development of single-cell RNA-sequencing technology provides a possibility to understand the functioning mechanism of the brain at the cellular level.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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brain tissue single-cell sequencing
Using single-cell sequencing to study the brain tissue single-cell transcriptome difference in aging, epilepsy, and mental disorders
Eligibility Criteria
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Inclusion Criteria
* Treatment-resistant epilepsy patients needing resection surgery
Exclusion Criteria
* Pregnancy
* Tumor
* Incomplete medical history, imaging and clinical diagnosis
18 Years
80 Years
ALL
No
Sponsors
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Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Principal Investigators
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Jianmin Zhang, M.D
Role: STUDY_CHAIR
Department of Neurosurgery
Junming Zhu, M.D
Role: PRINCIPAL_INVESTIGATOR
Department of Neurosurgery
Locations
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2ndAffiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
Countries
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Central Contacts
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Facility Contacts
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Jianmin Zhang, M.D
Role: primary
Other Identifiers
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2020-030
Identifier Type: -
Identifier Source: org_study_id
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