Current Use in Intensive Care Units by Intensivists of Antihypertensive Drugs

NCT ID: NCT04924946

Last Updated: 2021-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-06-01

Study Completion Date

2021-08-01

Brief Summary

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Multicenter, prospective and observational study of practices and impacts of the use of antihypertensive therapies in intensive medicine and intensive care

Detailed Description

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Multicenter, prospective observational cohort study on 200 patients, by doctor's questionnaire on the prescription of antihypertensive drugs in intensive care, follow-up over 72 hours of the prescription.

Conditions

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Antihypertensive Drugs in ICU

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Inventory of prescribing habits and detect any differences in efficacy and tolerance of antihypertensive drugs

* Time to monitor blood pressure values in target targets
* Need for administration of another antihypertensive drug
* Disappearance of organ failure attributable to hypertension
* Weaning from an extra-renal purification
* Weaning from mechanical ventilation
* Improved kidney function
* Iatrogenic hypotension
* Need for suspension of treatment
* Other side effect

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult patient
* Admitted to an intensive care unit
* Patient having presented a state of circulatory shock, defined by the need for continuous administration of a vasopressive amine for at least one hour, among: Noradrenaline, Adrenaline
* In whom the introduction of drug treatment for antihypertensive purposes is decided

Exclusion Criteria

* Patient admitted to intensive care for a hypertensive emergency (hypertensive surge or malignant arterial hypertension leading to organ dysfunction
* Patient who has already received at least one anti-hypertensive drug during his stay in intensive care
* Cerebro-injured patient, proven or suspected cerebral edema, head trauma \<1 month, decrease in cerebral perfusion measured
* Proven or suspected active bleeding
* Patient refusal of participation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Intensive Care Victor Dupouy Hospital

Argenteuil, , France

Site Status RECRUITING

Intensive Care Avicenne Hsopital

Bobigny, , France

Site Status RECRUITING

Intensive Care Louis Mourier Hospital

Colombes, , France

Site Status RECRUITING

Intensive Care Longjumeau Hospital

Longjumeau, , France

Site Status RECRUITING

Intensive Care Bichat Hospital

Paris, , France

Site Status RECRUITING

Intensive Care René Dubos Hospital

Pontoise, , France

Site Status RECRUITING

Intensive Care Tours Hospital

Tours, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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GAUDRY Stephane

Role: CONTACT

01 48 96 44 55

Facility Contacts

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PLANTEFEVE Gaëtan

Role: primary

0134232550

GAUDRY Stephane

Role: primary

01 48 96 44 55

FEDERICI Laura

Role: primary

01 47 60 61 62

LEMEUR Matthieu

Role: primary

01 64 54 33 33

SONNEVLLE Romain

Role: primary

01 40 25 77 03

THIAGARAJAH Abirami

Role: primary

01 30 75 40 40

PEREZ Yonathan

Role: primary

02 47 47 47 47

Other Identifiers

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APHP191137

Identifier Type: -

Identifier Source: org_study_id

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