Changes of Muramyl Dipeptide in Intestinal and Extra-intestinal Diseases
NCT ID: NCT04924686
Last Updated: 2021-06-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
600 participants
OBSERVATIONAL
2020-05-10
2023-08-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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Crohn's disease
The fecal and plasma were collected
Observational studies, no intervention
Observational studies, no intervention
Ulcerative colitis
The fecal and plasma were collected
Observational studies, no intervention
Observational studies, no intervention
Diabetes mellitus, type 2
The fecal and plasma were collected
Observational studies, no intervention
Observational studies, no intervention
Atherosclerotic cardiovascular disease
The fecal and plasma were collected
Observational studies, no intervention
Observational studies, no intervention
Colorectal cancer
The fecal and plasma were collected
Observational studies, no intervention
Observational studies, no intervention
Interventions
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Observational studies, no intervention
Observational studies, no intervention
Eligibility Criteria
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Inclusion Criteria
2. Patient able to give informed consent.
3. Patient with biopsy-proven CRC
4. Patient with biopsy-proven Crohn's disease (CD) or ulcerative colitis(UC), in the active phase.
5. patients with clinical diagnosed DM2
6. patients with ACVD:coronary angiography more than 50% stenosis in single or multiple vessels.
7. The age- and sex- matched health controls for each patient.
Exclusion Criteria
18 Years
70 Years
ALL
Yes
Sponsors
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National Natural Science Foundation of China
OTHER_GOV
Zhujiang Hospital
OTHER
Responsible Party
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Hongwei Zhou
Proffessor
Principal Investigators
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Hongwei Zhou, professor
Role: PRINCIPAL_INVESTIGATOR
Zhujiang Hospital, Guangzhou, Guangdong
Locations
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Zhujiang hospital
Guangzhou, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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References
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Philpott DJ, Sorbara MT, Robertson SJ, Croitoru K, Girardin SE. NOD proteins: regulators of inflammation in health and disease. Nat Rev Immunol. 2014 Jan;14(1):9-23. doi: 10.1038/nri3565. Epub 2013 Dec 13.
Other Identifiers
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ZhujiangH-1
Identifier Type: -
Identifier Source: org_study_id
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