Evaluation of the Performance of Epidural Analgesia After Major Abdominal Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

69 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-14

Study Completion Date

2021-12-11

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery. However, several studies have reported a failure rate of APT of up to 30%. Its efficacy regarding pain control during coughing and mobilization is also inconsistent, with correct analgesia found in only 60% of cases in a Scandinavian multicenter cohort. Inadequate Epidural analgesia may be associated with more postoperative complications. This finding prompts a study in our institution to evaluate the performance of epidural analgesia after major open abdominal surgery.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Postoperative Analgesia in Abdominal Surgery: a Medico-economic Study

NCT01470846

Extended Ileal Resection Under Laparotomy Total Proctocolectomy Under Laparotomy Colectomy Left/Right/Total Under Laparotomy +3 more

TERMINATED PHASE4

Prospective, Randomised, Single-Blinded, Monocentric Clinical Study to Compare Postoperative Analgesia and Outcome After Combined Paravertebral and Intrathecal Versus Thoracic Epidural Analgesia for Thoracotomy

NCT00493909

Pain, Postoperative

COMPLETED PHASE4

Persistent Postoperative Pain After Major Emergency Abdominal Surgery

NCT04508465

Chronic Postoperative Pain

UNKNOWN

Comparison of Analgesic Methods, and Their Effects on Patient Recovery, Following Liver Surgery

NCT01042054

Postoperative Pain

COMPLETED NA

Postoperative Opioid-Sparing Effect of a Pecto-Intercostal Fascial Block and Opioid-Free Anesthesia.

NCT04854577

Opioid Free Anaesthesia Opioid Anaesthesia

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Epidural analgesia is widely used for the treatment of acute postoperative pain, and currently represents the gold standard after open major abdominal surgery. However, several studies have reported a failure rate of APT of up to 30%. Its efficacy regarding pain control during coughing and mobilization is also inconsistent, with correct analgesia found in only 60% of cases in a Scandinavian multicenter cohort. Inadequate Epidural analgesia may be associated with more postoperative complications. This finding prompts a study in our institution to evaluate the performance of epidural analgesia after major open abdominal surgery.

Epidural analgesia does not guarantee total control of acute postoperative pain after major open abdominal surgery. The performance of epidural analgesia could vary according to predisposing factors and postoperative days. Inadequate epidural analgesia could be associated with greater morbidity after open major abdominal surgery.

In order to evaluate the performance of epidural analgesia after major open abdominal surgery, a prospective observational monocentric scheme seems relevant. The evaluation will be clinical based on questioning and a brief medical examination during the early postoperative phase of the operated patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Epidural Analgesia After Major Open Abdominal Surgery

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients

Open major abdominal surgery patient (predicted operative time ≥ 2 hours) with Peridural Analgesia accepted

postoperative pain assess

Intervention Type OTHER

numerical pain scale and Metameric levels of cold insensitivity

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

postoperative pain assess

numerical pain scale and Metameric levels of cold insensitivity

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

numerical pain scale

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Major abdominal surgery patient operated by laparotomy (predicted operative time ≥ 2 hours)
* epidural analgesia accepted

Exclusion Criteria

* Minor or protected patient
* Patients under guardianship, curatorship or safeguard of justice
* Pregnant or breastfeeding woman
* Contraindication or refusal of epidural analgesia
* Failure of the initial placement of the epidural catheter
* Major intraoperative complication requiring continued postoperative sedation

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No