Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

47 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-09

Study Completion Date

2024-04-01

Brief Summary

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The purpose of this study is to evaluate and compare the changes by two modalities: Imaging by Strain by Speckle Tracking and Magnetic Resonance versus soluble markers of cardiac dysfunction as early predictors of cardio-toxicity in cancer patients receiving low or high doses of radiotherapy.

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Detailed Description

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Conditions

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Radiotherapy; Complications Cardiotoxicity Cancer Lung Cancer Breast Cancer Esophageal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* ≥18 year-old patients
* With histologically confirmed thoracic cancer (breast, esophagus or lung)
* Recommendation of thoracic radiotherapy (RT) with curative intent
* With or without chemotherapy
* All patients must be able to read and understand Spanish
* All patients must sign informed consent form.

Exclusion Criteria

* Patients with no medical records,
* Pregnant
* Previously diagnosed with severe left ventricular dysfunction or a cardiac insufficiency
* Patients with metastatic disease and indication of palliative RT
* Patients with significant comorbidities associated to a \<5 year life expectancy.
* Patients previously treated with thoracic RT

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No