BEOVU Versus Eylea in the Treatment of Age-related Macular Neovascular Degeneration

NCT ID: NCT04882956

Last Updated: 2021-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-05

Study Completion Date

2022-03-31

Brief Summary

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Age-Related macular neovascularization degeneration occur is a vision threatening condition. The investigators compare the efficacy of BEOVU and Eylea intravitreal treatment in the management.

Detailed Description

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Baseline ,and postoperative 1 ,6 and 12 months full ophthalmic examination was done. Procedure included randomized intravitreal injection of Brolucizumab (BEOVU®, Genentech, South Francisco, CA) and of aflibercept (Eylea; Regeneron, Tarrytown,NY)

Conditions

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Macula Lutea Degeneration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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BEOVU

Intravitreal injection of BEOVU 3 loading injections ( monthly) then every 3 months

Group Type ACTIVE_COMPARATOR

intravitreal injection

Intervention Type DRUG

Brolucizumab-Dbll intravitreal injection

Eylea

Intravitreal injection of Eylea 3 loading injections ( monthly) then every 3 months

Group Type ACTIVE_COMPARATOR

intravitreal injection

Intervention Type DRUG

Aflipercept intravitreal injection

Interventions

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intravitreal injection

Brolucizumab-Dbll intravitreal injection

Intervention Type DRUG

intravitreal injection

Aflipercept intravitreal injection

Intervention Type DRUG

Other Intervention Names

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BEOVU Eylea

Eligibility Criteria

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Inclusion Criteria

* • Age-Related macular neovascularization degeneration

Exclusion Criteria

* other causes of macular neovascularization degeneration
* other macular diseases
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Tarek Roshdy mohamed Mahgoub ELhamaky

Professor (associate)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tarek Elhamaky, MD

Role: PRINCIPAL_INVESTIGATOR

Benha University

Locations

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INMC

Abu Dhabi, , United Arab Emirates

Site Status RECRUITING

Countries

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United Arab Emirates

Central Contacts

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Tarek R Elhamaky, MD

Role: CONTACT

+97126324200

Tarek Elhamaky, MD

Role: CONTACT

Facility Contacts

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TAREK R ELHAMAKY, MD

Role: primary

Other Identifiers

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Hamaky11

Identifier Type: -

Identifier Source: org_study_id

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