Efficacy of Retreatments With Intravitreal Bevacizumab

NCT ID: NCT00406744

Last Updated: 2024-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-05-31

Study Completion Date

2006-11-30

Brief Summary

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Choroidal neovascularization is a leading cause of visual loss in people older than 60 years and for its treatment there had been performed multicentric studies with Lucentis (Ranibizumab) with a significant improval of visual acuity. In our institution we evaluated efficacy of bevacizumab in several pathologies but we dont know what would be the results if we use the same dose several times. Our purpose was to determine the efficacy of bevacizumab for improve or stabilize visual acuity with two or more intravitreal inyections of bevacizumab.

Detailed Description

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Conditions

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Age Related Macular Degeneration Choroidal Neovascularization

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Intravitreal injection of Bevacizumab

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* \* Any visual acuity

* OCT: Central foveal thickness greater than 300 u or with evidence of subretinal fluid.
* Active angiogram leakage

Exclusion Criteria

* \* Basal Inflammatory disease

* Endoftalmitis history
* Lesions bigger than 5400 u or with scarring greater than 50% of lesion.
Minimum Eligible Age

60 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Asociación para Evitar la Ceguera en México

OTHER

Sponsor Role lead

Principal Investigators

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Veronica Kon-Jara, MD

Role: PRINCIPAL_INVESTIGATOR

Asociación para Evitar la Ceguera en México

Locations

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Asociacion para Evitar la Ceguera en Mexico

Mexico City, Mexico City, Mexico

Site Status

Countries

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Mexico

Other Identifiers

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APEC-0012

Identifier Type: -

Identifier Source: org_study_id

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