Effect of the PIPAC on the Survival Rate of Patients With Peritoneal Carcinomatosis of Gastric Origin

NCT ID: NCT04879953

Last Updated: 2021-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-01

Study Completion Date

2020-12-31

Brief Summary

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Pressurised intraperitoneal aerosol chemotherapy is a new surgical technique, developed for the treatment of initially unresectable peritoneal carcinomatosis. The objective of this study was to compare the results of PIPAC associated with systemic chemotherapy with those of systemic chemotherapy alone in patients with gastric peritoneal carcinomatosis without metastasis other than peritoneal, and WHO performance status \<3.

Detailed Description

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Conditions

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Carcinomatosis, Peritoneal

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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PIPAC CHEM

PIPAC associated with systemic chemotherapy

PIPAC with systemic chemotherapy

Intervention Type DRUG

PIPAC procedures were performed every 6 to 8 weeks, alternating with systemic chemotherapy, replacing a cycle of intravenous chemotherapy.

ONLY CHEM

systemic chemotherapy alone

Systemic chemotherapy alone

Intervention Type DRUG

Intravenous chemotherapy

Interventions

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PIPAC with systemic chemotherapy

PIPAC procedures were performed every 6 to 8 weeks, alternating with systemic chemotherapy, replacing a cycle of intravenous chemotherapy.

Intervention Type DRUG

Systemic chemotherapy alone

Intravenous chemotherapy

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients 18 years or over
* Patients with adenocarcinoma-type gastric non-resectable péritonéale carcinomatosis.
* Patients without metastasis other than peritoneal.
* WHO performance status \<3
* Patients treated either with PIPAC administered in alternation with systemic chemotherapy (PIPAC\_CHEM) or by systemic chemotherapy alone (ONLY\_CHEM)
* Patient informed

Exclusion Criteria

\- Patients opposed
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Association Francaise de Chirurgie

OTHER

Sponsor Role lead

Responsible Party

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Pr Catherine Arvieux

Professeur

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Catherine Arvieux

Role: PRINCIPAL_INVESTIGATOR

Grenoble Hospital

Locations

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CHUGA

Grenoble, , France

Site Status

Countries

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France

Other Identifiers

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PIPAC

Identifier Type: -

Identifier Source: org_study_id

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