Behavioral Interventions to Reduce Particulate Matter Exposure in Patients With COPD
NCT ID: NCT04878367
Last Updated: 2023-04-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
120 participants
INTERVENTIONAL
2021-06-01
2023-03-31
Brief Summary
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Detailed Description
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A total of 120 COPD patients will be recruited from three institutions: Asan Medical Center, Severance Hospital, and Ilsan Paik Hospital. (60/30/30 expected) A panel of COPD patients is established to conduct prospective studies, and measures to mediate recurrence and deterioration of adult chronic respiratory diseases due to exposure to fine dust are presented. Improvement of the lifestyle of the arbitration forces. Detailed research methods such as air purifier support are presented in the research plan.
In addition, a fine dust measurement researcher visits each household to measure indoor fine dust concentration. The measurement method of fine dust concentration will be using the process test method, IoT-based sensors, and direct-to-read measuring devices to measure Air Korea's air pollution. Detailed visit timing and methods are carried out in the manner specified in the research plan.
We collect sputum at every visit and blood at the last visit.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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COPD_E
COPD patients with intervention
Five active practices of living rules for responding to fine dust.
1. Check the fine dust weather forecast
2. Check the operation time and filter of the air purifier
3. Window ventilation
4. Inhalant is used or not
5. Bad fine dust: Refrain from going out
COPD_C
COPD patients without intervention
No interventions assigned to this group
Interventions
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Five active practices of living rules for responding to fine dust.
1. Check the fine dust weather forecast
2. Check the operation time and filter of the air purifier
3. Window ventilation
4. Inhalant is used or not
5. Bad fine dust: Refrain from going out
Eligibility Criteria
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Inclusion Criteria
* Waste function test results show FEV1/FVC\<0.7, FEV1 \<80% of forecast
Exclusion Criteria
* Older people over 80 years of age.
* People with no respiratory symptoms with mMRC 0.
* Who doesn't understand a simple explanation for fine dust exposure devices.
* Someone who disagrees with the study.
40 Years
80 Years
ALL
No
Sponsors
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Asan Medical Center
OTHER
Responsible Party
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Sei Won Lee
associate professor
Principal Investigators
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Sei won Lee
Role: PRINCIPAL_INVESTIGATOR
Seoul Asan Hospital
Locations
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Asan Medical Center
Seoul, , South Korea
Countries
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References
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Ji HW, Kang J, Kim HC, Jung J, Lee SJ, Jung JY, Lee SW. The association between cumulative exposure to PM2.5 and DNA methylation measured using methyl-capture sequencing among COPD patients. Respir Res. 2024 Sep 9;25(1):335. doi: 10.1186/s12931-024-02955-3.
Kang J, Kim HC, Jang Y, Lee JB, Lee JS, Oh YM, Ji HW, Jung JY, Lee SW. Randomised controlled trial of a behavioural intervention to reduce exposure to PM2.5 in patients with COPD. Environ Int. 2023 Nov;181:108286. doi: 10.1016/j.envint.2023.108286. Epub 2023 Oct 24.
Kang J, Jung JY, Huh JY, Ji HW, Kim HC, Lee SW. Behavioral interventions to reduce particulate matter exposure in patients with COPD. Medicine (Baltimore). 2021 Dec 10;100(49):e28119. doi: 10.1097/MD.0000000000028119.
Other Identifiers
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2021-0956
Identifier Type: -
Identifier Source: org_study_id
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