Cardiovascular Responses in Adolescent Idiopathic Scoliosis Girls

NCT ID: NCT04868331

Last Updated: 2022-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-18

Study Completion Date

2022-03-12

Brief Summary

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The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for AIS girls performing E-Fit will behave in the same way as compared to healthy controls. We hypothesise that 1) the metabolic demand and exercise intensity of E-Fit exercise intervention is equivalent to moderate-to-vigorous level; and 2) AIS girls have different cardiovascular responses as compared to healthy controls

Detailed Description

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AIS girls and age- and gender-matched healthy controls will perform the E-Fit exercise intervention for two trials and gas exchange parameters including oxygen consumption (VO2) and carbon dioxide production (VCO2) will be taken continuously during the exercise. Comparison of VO2 and VCO2 between AIS and healthy controls when performing E-Fit exercise will be made.

Conditions

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Adolescent Idiopathic Scoliosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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AIS girls

Girls between the ages of 10-16 will be recruited if they have a diagnosis of AIS.

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Two trials of 7-min High Intensity Interval Training (HIIT) with 12 different exercises. Each exercise lasts for 30 seconds continuously with 10 seconds rest interval.

Healthy Controls

Healthy adolescent girls matched in age and puberty maturity without spinal deformity

Group Type ACTIVE_COMPARATOR

Exercise

Intervention Type BEHAVIORAL

Two trials of 7-min High Intensity Interval Training (HIIT) with 12 different exercises. Each exercise lasts for 30 seconds continuously with 10 seconds rest interval.

Interventions

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Exercise

Two trials of 7-min High Intensity Interval Training (HIIT) with 12 different exercises. Each exercise lasts for 30 seconds continuously with 10 seconds rest interval.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Cobb angle greater or equal to 15 degree
* Cleared for physical activity by doctor

Exclusion Criteria

* Cobb angle greater or equal to 40 degree, or
* Scoliosis with any known etiology, scoliosis with skeletal dysplasia, know endocrine and connective tissue abnormalities, or
* Known heart condition or other diseases that could affect the safety of exercise, or
* Eating disorders or GI malabsorption disorders, or
* Currently taking medication that affects bone or muscle metabolism
Minimum Eligible Age

10 Years

Maximum Eligible Age

16 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese University of Hong Kong

OTHER

Sponsor Role collaborator

Tung Wah College

OTHER

Sponsor Role lead

Responsible Party

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Rufina Lau

Senior Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rufina Lau, MSc

Role: PRINCIPAL_INVESTIGATOR

Tung Wah College

Locations

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Tung Wah College

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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2019-02-52-SRG190201

Identifier Type: -

Identifier Source: org_study_id

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