Investigation of the Effects of Selective Exercise Training in Multiple Sclerosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-15

Study Completion Date

2020-06-15

Brief Summary

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Selective exercise programs specific to muscle groups, with the workload to be done in line with the muscle's own structure, can enable more strength to be released with less fatigue in MS, and this increase in strength can increase balance and functional activities. to determine the effects of type training (selective exercise training), eccentric and concentric training on function, balance, fatigue and muscle architecture.

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Detailed Description

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Recovery and enhancement of muscle function in MS is one of the main goals in physiotherapy and rehabilitation. In literature studies, it is stated that eccentric and concentric exercises are effective exercise approaches in increasing strength and reducing fatigue. However, the best exercise method is not yet clear in terms of providing better performance adaptation with less fatigue. Considering the architectural features of the lower extremity muscles, it is aimed to increase the angle of pennation with programs that include concentric strengthening of the quadriceps, gastro-soleus and gastrocnemius muscles, which are suitable muscle groups to produce large forces by design. With programs that include eccentric strengthening of the hamstring and tibialis anterior muscles that function in a wide range of motion and have high excursion ability, it is aimed to increase fiber length.

Conditions

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Multiple Sclerosis Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Selective training

selective training on lower extremity for 3 days/week

Group Type EXPERIMENTAL

exercise

Intervention Type OTHER

exercise training for 8 weeks

Downhill walking

downhill walking training on the treadmill for 2 days/week

Group Type EXPERIMENTAL

exercise

Intervention Type OTHER

exercise training for 8 weeks

Uphill walking

uphill walking training on the treadmill for 2 days/week

Group Type EXPERIMENTAL

exercise

Intervention Type OTHER

exercise training for 8 weeks

Interventions

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exercise

exercise training for 8 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Between the ages of 18-50,
* With an Extended Disability Status Scale (EDSS) score of 4 or less,
* No regular exercise habit
* Able to walk on the treadmill,
* No pregnancy,
* Not receiving corticosteroid treatment in the last month,
* Fampridine etc. in the last 1 month. not taking medication,
* Patients who have not received Botox treatment in the last 6 months