Marijuana Use, Strength Training, and Alcohol Consumption (MUSTAC) Study

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-28

Study Completion Date

2022-05-10

Brief Summary

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Self-medication of pain by consuming alcohol and marijuana is common. However, the research regarding pain as a determinant for alcohol and marijuana use has relied on laboratory pain induction paradigms with limited clinical relevance. The study will assess demand for alcohol and marijuana before and after delayed onset muscle soreness (DOMS) induction in co-users. This will provide a clinically relevant, but time-limited, model for the effects of musculoskeletal pain on demand.

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Detailed Description

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Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Delayed Onset Muscle Soreness Induction

Participants will complete an exercise session designed to induce delayed onset muscle soreness in the biceps

Group Type EXPERIMENTAL

Eccentric Biceps Flexion

Intervention Type BEHAVIORAL

Muscle lengthening biceps exercise

Sham Delayed Onset Muscle Soreness Induction

Participants will complete an exercise session that is unlikely to induce delayed onset muscle soreness in the biceps

Group Type SHAM_COMPARATOR

Concentric Biceps Flexion

Intervention Type BEHAVIORAL

Muscle shortening biceps exercise

Interventions

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Eccentric Biceps Flexion

Muscle lengthening biceps exercise

Intervention Type BEHAVIORAL

Concentric Biceps Flexion

Muscle shortening biceps exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 21 years;
* English-speaking
* Self-identify as White/Caucasian or Black/African American
* Own a smartphone with cellular/data plan
* Regularly co-use alcohol and smoked marijuana as indicated by scores of ≥3 on item 1 of the CUDIT-R and AUDIT.
* Willing and able to give informed consent

Exclusion Criteria

* Participation in biceps-specific conditioning program in the past 6 months\*
* Self-reported wrist/hand, elbow, or shoulder pain the past 3 months
* Chronic medical condition that may affect pain perception (e.g. diabetes, fibromyalgia, headaches)
* Self-reported kidney dysfunction, muscle damage, or major psychiatric disorder
* Medical marijuana prescription
* Consumption of marijuana using only non-inhalational methods (e.g. edibles, tinctures, or cannabidiol oil)
* Score of ≥ 10 on Patient Health Questionnaire-9 (moderate depression)
* Women who are pregnant, trying to become pregnant, or breastfeeding

Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes