Antihypertensive Therapy in Patients With Comorbidities

NCT ID: NCT04791046

Last Updated: 2021-03-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2021-03-30

Brief Summary

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A retrospective analysis

Detailed Description

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This retrospective study will be performed using all-Russian nationwide database of anonymized medical health claims and administrative data. The database holds information on diagnoses, patient data, medications, results of examinations, laboratory values, and genomic information, visits, follow up and outcomes. Participating health care organizations include a mix of hospital, primary care, and specialty treatment providers spanning a wide range of geographies, age groups, and income levels.

This study will analyze of outcomes according to comorbidity and antihypertensive drug prescriptions. The study will include patients who were first diagnosed with hypertension, attended the hospital as an outpatient due to hypertension, and received their antihypertensive prescription as an outpatient. To be eligible for inclusion, patients must have had comorbidities and outpatient visits or hospitalizations (for any indication) during the 3-years. The study will focused on comorbidities for choice of antihypertensive drug therapy: diabetes mellitus, dyslipidemia, gout/hyperuricemia, heart diseases, cerebrovascular diseases, and renal diseases.

We going to analyze the EMR of patients who had hypertension and comorbidities by CDSS (MedicBK) utilizing a core laboratory.

Conditions

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Adherence to Personalized EBM Antihypertensive Drug Prescriptions for Patients With Hypertension and Comorbidities in Everyday Clinical Practice

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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By CDSS (MedicBK) Analysis

antihypertensive therapy

Intervention Type DRUG

Personalized evidence-based antihypertensive therapy in patients with comorbidities

General practice

antihypertensive therapy

Intervention Type DRUG

Personalized evidence-based antihypertensive therapy in patients with comorbidities

Interventions

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antihypertensive therapy

Personalized evidence-based antihypertensive therapy in patients with comorbidities

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

patients who were first diagnosed with hypertension, attended the hospital as an outpatient due to hypertension, and received their antihypertensive prescription as an outpatient. To be eligible for inclusion, patients had to have comorbidities and outpatient visits or hospitalizations (for any indication) during the 3-years.

Exclusion Criteria

No
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Center for New Medical Technologies, Novosibirsk, Russia

OTHER

Sponsor Role collaborator

I.M. Sechenov First Moscow State Medical University

OTHER

Sponsor Role collaborator

Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health

OTHER

Sponsor Role collaborator

University of Rochester

OTHER

Sponsor Role collaborator

Center of Personalized Medicine, Pirogova

OTHER

Sponsor Role lead

Responsible Party

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Evgeny Pokushalov

Director for research and development

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Evgeny Pokushalov, Prof. MD PhD

Role: PRINCIPAL_INVESTIGATOR

Center for New Medical Technologies, Novosibirsk, Russia

Locations

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Evgeny Pokushalov

Novosibirsk, , Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Evgeny Pokushalov, Prof. MD PhD

Role: CONTACT

89139254858

Svetlana Kozlova, MD

Role: CONTACT

+79213360508

Facility Contacts

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Evgeny Pokushalov, Prof. MD PhD

Role: primary

89139254858

Other Identifiers

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20210308

Identifier Type: -

Identifier Source: org_study_id

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