MedDataX Logo

Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits

NCT ID: NCT04788030

Last Updated: 2021-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

37 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-01

Study Completion Date

2021-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible. Low donor site morbidity and absence of additional costs are favorable advantages compared to autografts or conduits. 37 patients with 43 defects of proper palmar digital nerves were retrospectively enrolled. Primary repair by MVCs was performed in 22 cases while 21 underwent secondary reconstruction. Recovery of sensibility was assessed by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilaments (SWM). Results were compared with contralateral side serving as intraindividual control. Outcome data were stratified according to international guidelines and evaluated for differences in terms of age, gap length, time of reconstruction and concomitant injuries.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Muscle-in-vein Conduits for Digital Nerve Reconstruction

NCT01958632

Sensory Recovery
COMPLETED

A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction

NCT01826539

Soft Tissue Defect of the Finger
COMPLETED NA

A Phase I Trial of a Novel Synthetic Polymer Nerve Conduit 'Polynerve' in Participants With Sensory Digital Nerve Injury

NCT02970864

Injury of Nerves at Wrist and Hand Level
COMPLETED NA

Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence

NCT06142929

Dupuytren's Disease
RECRUITING

Evaluation of Complete Median Nerve Transection With Clinical, Electroneuromyographic and Diffusion Tensor Imaging

NCT02672631

Wound, Healed (Morphologic Abnormality) Injury of Median Nerve
UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Peripheral Nerve Injury Upper Limb

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Digital nerve reconstruction with muscle-in-vein conduits

Nerve reconstruction

Intervention Type OTHER

Nerve bridging with muscle-in-vein conduits

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Nerve reconstruction

Nerve bridging with muscle-in-vein conduits

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

\- Patients with reconstruction of digital nerves with muscle-in-vein conduits

Exclusion Criteria

* Subtotal or total amputations
* pre-existing neurological disorders (e.g. polyneuropathy)
* symptoms of nerve entrapment
Minimum Eligible Age

6 Years

Maximum Eligible Age

72 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

BG Trauma Center Tuebingen

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

PD Dr. Theodora Wahler

Chief of the Department of Hand, Plastic and Aesthetic Surgery, medius Hospital Nürtingen

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

650/2018BO2-1

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Electrophysiological Study of Berrettini Anastomosis
NCT06458751 COMPLETED NA
Ulnar Nerve Neurotization After Ulnar Nerve Injury
NCT05283785 UNKNOWN
Nerve Morphology in Diabetic Patients
NCT00856011 COMPLETED
Electrophysiological Changes Based on the Palmaris Longus
NCT04619849 UNKNOWN NA
Promoting Healing of Nerves Through Electrical Stimulation
NCT04662320 ACTIVE_NOT_RECRUITING NA
Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair
NCT01809002 COMPLETED PHASE3
Vitamin B12 and Dextrose for Median Nerve Hydrodissection
NCT05423028 RECRUITING NA
Electrical Nerve Stimulation of the Ulnar Nerve
NCT02566616 WITHDRAWN NA
Efficacy of Local Direct Median Nerve Block
NCT04453462 COMPLETED NA
Multimodal Approach of Electrotherapy Versus Nerve Flossing Technique in Patient With Carpal Tunnel Syndrome
NCT05164237 UNKNOWN NA
Kirschner Wire and Pull-out Wire Fixation for the Treatment of Bony Mallet Finger
NCT01072760 COMPLETED NA
Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome
NCT05788471 UNKNOWN NA
Conditioning Electrical Stimulation to Improve Outcomes in Carpal Tunnel Syndrome
NCT04191538 COMPLETED PHASE1/PHASE2
Use of a Nerve Regeneration Conduit (NerVFIX®) in the Treatment of Nerve Section of the Wrist
NCT05199155 TERMINATED PHASE2
Nerve Entrapment in Diabetic Patients
NCT00775333 COMPLETED
Efficacy of Combining Ultrasound-Guided Needle Release of Transverse Carpal Ligament and Median Nerve Dextrose Water Hydrodissection for Carpal Tunnel Syndrome
NCT07324005 NOT_YET_RECRUITING NA
Chitosan Nerv Tube for Primary Repair of Traumatic Sensory Nerve Lesions of the Hand
NCT02372669 UNKNOWN NA
A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options
NCT00948025 TERMINATED NA
Short Term Efficacy of 5% Dextrose Injection With Ultrasound Guided Nerve Hydrodissection Method in CTS
NCT06189651 COMPLETED NA
Ulnar Nerve Deep Branch Compression by a Ganglion
NCT01994434 COMPLETED NA
Comparative Study of Two Ultrasound-guided Percutaneous Neuromodulation Protocols on Maximal Handgrip Strength.
NCT07098130 COMPLETED NA
The Volume Effect of Nerve Hydrodissection for Carpal Tunnel Syndrome
NCT03381521 COMPLETED NA
Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome
NCT01972165 COMPLETED NA
Percutaneous Needle Electrolysis Versus Surgery in the Treatment of Carpal Tunnel Syndrome
NCT04216147 COMPLETED NA
Effects of Neuromobilization on Median Nerve
NCT05569395 COMPLETED NA