Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse

NCT ID: NCT04788004

Last Updated: 2026-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

733 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-08

Study Completion Date

2026-07-20

Brief Summary

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The goals of this study are to provide a scientific understanding of recovery and relapse, as well as to identify novel targets for future relapse prevention interventions.

Detailed Description

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The study will characterize long-term trajectories of recovery from alcohol use including the associated changes in psychosocial functioning and relapse status. By using an accelerated longitudinal design, competing neurobehavioral decision systems (CNDS) functioning (measured using delay discounting), psychosocial functioning, and relapse will be characterized over a 12-year period for individuals in alcohol use disorder (AUD) recovery.

Conditions

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Alcohol Use Disorder

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cohort 1

Participants in this group started their recovery process \< 1 year ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 2

Participants in this group started their recovery process 1 to \<2 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 3

Participants in this group started their recovery process 2 to \<3 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 4

Participants in this group started their recovery process 3 to \<4 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 5

Participants in this group started their recovery process 4 to \<5 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 6

Participants in this group started their recovery process 5 to \<6 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 7

Participants in this group started their recovery process 6 to \<7 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 8

Participants in this group started their recovery process 7 to \<8 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 9

Participants in this group started their recovery process 8 to \<9 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Cohort 10

Participants in this group started their recovery process 9 to \<10 years ago

Online survey

Intervention Type OTHER

There are no interventions planned for this study. This is an observational study only.

Interventions

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Online survey

There are no interventions planned for this study. This is an observational study only.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. be ≥18 yrs old
2. meet lifetime DSM-5 AUD criteria
3. have a Recovery Initiation Date less than 10 years prior to the time of enrollment
4. be able to read independently
5. be free of legal problems that could limit participation
6. reside in the U.S.
7. anticipate continued Internet access (to ensure ongoing contact and data collection)
8. be a registrant of the International Quit and Recovery Registry (IQRR)

Exclusion Criteria

* Minors will not be included
* Prisoners will not be included. If participants become incarcerated during this study, they will not be contacted to complete assessments during their incarceration. If the incarcerations ends during the study, they may be contacted to participate in assessments.
* Adults who are not capable of consenting on their own behalf
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Virginia Polytechnic Institute and State University

OTHER

Sponsor Role lead

Responsible Party

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Jungmeen Kim-Spoon

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jungmeen Kim-Spoon, PhD

Role: PRINCIPAL_INVESTIGATOR

Virginia Polytechnic Institute and State University

Allison Tegge, PhD

Role: PRINCIPAL_INVESTIGATOR

Virginia Polytechnic Institute and State University

Locations

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Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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IQRR- Longitudinal Study

Identifier Type: -

Identifier Source: org_study_id

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