An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

300000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2021-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this protocol, the investigators present methods and preliminary results from the PLATFORM-CVD Study, an EHR-based multicenter cohort. This study will focus on assessing the distribution of major cerebrovascular diseases, determining the risk factors associated with disease incidence and worse in-hospital outcomes, as well as describing the quality of care. Data from this cohort will be used to develop suitable prediction models for cerebrovascular diseases using real-world data and to understand how outcomes for cerebrovascular diseases would change with quality improvement interventions.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

A Registry Study of Microcirculation Disorder After Cerebral Small Vessel Disease and Ischemic Stroke

NCT06077305

Cerebral Small Vessel Diseases Ischemic Stroke

NOT_YET_RECRUITING

Early Neurological Trajectory and Clinical Outcomes in Brain Acute Ischemic Stroke

NCT06170086

Stroke, Acute

ACTIVE_NOT_RECRUITING

Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct Trial

NCT07118345

Stroke, Ischemic Cerebral Edema

RECRUITING NA

Clinical Outcomes Following Primary Intracerebral Hemorrhage

NCT06548737

Stroke Intracerebral Hemorrhage

RECRUITING

Stopping Cognitive Decline and Dementia by Fighting Covert Cerebral Small Vessel Disease

NCT05306834

Cerebral Small Vessel Diseases Stroke Dementia

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Adherence to healthcare quality measures is needed to reduce the burden of cerebrovascular disease and improve clinical outcomes. Electronic health records (EHRs) can facilitate the standardization of care provision and the improvement of disease prediction and prevention. Although the EHRs in clinical settings are increasingly prevalent in China, they are rarely used for healthcare research. the investigators aimed to conduct an EHR-based registry study to improve the healthcare and outcomes for cerebrovascular diseases.

Twenty-four hospitals were enrolled in the PLATFORM-CVD Study in January 2018. Data collection began on February 1st, 2019. Historical data from January 2017 are abstracted first and prospective data are continuously reported until May 20th, 2020. Data were abstracted from the medical records, including hospital information system, laboratory information management system, and picture archiving and communication systems by an extract-transform-load tool. The EHR system included diagnostic information for cerebral infarctions (I63), nontraumatic intracerebral hemorrhages (I61), nontraumatic subarachnoid hemorrhages (I60), transient cerebral ischemic attacks and related syndromes (G45), intracranial and intraspinal phlebitis and thrombophlebitis (G08), vascular dementia (F01), and other aneurysms (I72). The quality of stroke care was assessed by 21 evidence-based performance measures. In-hospital outcomes were calculated including mortality, length of stay, and costs.

The PLATFORM-CVD Study leverages EHRs to better understand incident cerebrovascular diseases in China. Data from this cohort will serve as a unique platform for quality assessment and improvement for acute treatment and secondary prevention of cerebrovascular diseases, as well as in-hospital outcome risk predictions and health economic evaluations.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Stroke Cerebrovascular Diseases Cerebral Infarction Cerebral Hemorrhage Transient Ischemic Attack Subarachnoid Hemorrhage

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients were included in the registry if they were hospitalized with a primary diagnose of：
* cerebral infarction (I63)
* nontraumatic intracerebral hemorrhage (I61)
* nontraumatic subarachnoid hemorrhage (I60)
* transient cerebral ischemic attack and related syndromes (G45)
* intracranial and intraspinal phlebitis and thrombophlebitis (G08)
* vascular dementia (F01)
* other aneurysms (I72)