Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.

NCT ID: NCT04767269

Last Updated: 2021-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2021-01-31

Brief Summary

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Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.

Detailed Description

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To evaluate and compare the efficacy of 0.2% cuminum cyminum herbal preparation against 0.2% chlorhexidine by various clinical parameters i.e. plaque index, gingival index and sulcus bleeding index.

Conditions

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Chronic Gingivitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

1. Group phase A
2. Group phase B
3. Group phase C
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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cuminum cyminum mouthwash

cuminum cyminum mouthwash in chronic gingivitis patients

Group Type EXPERIMENTAL

Cuminum Cyminum

Intervention Type DRUG

Cuminum Cyminum mouthwash in chronic gingivitis patients

herbal mouthwash

herbal mouthwash in chronic gingivitis patients

Group Type ACTIVE_COMPARATOR

herbal Mouthwash

Intervention Type DRUG

herbal mouthwash in chronic gingivitis patients

Interventions

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Cuminum Cyminum

Cuminum Cyminum mouthwash in chronic gingivitis patients

Intervention Type DRUG

herbal Mouthwash

herbal mouthwash in chronic gingivitis patients

Intervention Type DRUG

Other Intervention Names

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Cuminum Cyminum mouthwash herbal mouthwash in chronic gingivitis patients

Eligibility Criteria

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Inclusion Criteria

* volunteers with minimum 20 natural teeth without restoration.
* cooperative
* motivated and committed to participate in the trial period.

Exclusion Criteria

* Antibiotic or anti-inflammatory therapy in previous month.
* Any known allergy/ hypersensitivity to any product used in trial.
Minimum Eligible Age

23 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Maharishi Markendeswar University (Deemed to be University)

OTHER

Sponsor Role lead

Responsible Party

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DR SURINDER SACHDEVA

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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surinder sachdeva, M.D.S.

Role: PRINCIPAL_INVESTIGATOR

PROFESSOR

Locations

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Department of Periodontology, M.M. College of Dental Sciences and Research.

Ambāla, Haryana, India

Site Status

Countries

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India

References

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Southern EN, McCombs GB, Tolle SL, Marinak K. The comparative effects of 0.12% chlorhexidine and herbal oral rinse on dental plaque-induced gingivitis. J Dent Hyg. 2006 Winter;80(1):12. Epub 2006 Jan 1.

Reference Type BACKGROUND
PMID: 16451766 (View on PubMed)

Salgado AD, Maia JL, Pereira SL, de Lemos TL, Mota OM. Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans. J Appl Oral Sci. 2006 Jun;14(3):162-6. doi: 10.1590/s1678-77572006000300003.

Reference Type BACKGROUND
PMID: 19089066 (View on PubMed)

Bettaieb I, Bourgou S, Wannes WA, Hamrouni I, Limam F, Marzouk B. Essential oils, phenolics, and antioxidant activities of different parts of cumin (Cuminum cyminum L.). J Agric Food Chem. 2010 Oct 13;58(19):10410-8. doi: 10.1021/jf102248j.

Reference Type BACKGROUND
PMID: 20809647 (View on PubMed)

Other Identifiers

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MaharishiMu2012

Identifier Type: -

Identifier Source: org_study_id

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