Fibromyalgia Outcome Research Trial Evaluating Synergistic Suppression of HSV-1

NCT ID: NCT04748705

Last Updated: 2022-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

422 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-03

Study Completion Date

2022-08-05

Brief Summary

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Randomized, double-blind, placebo-controlled, 16-week study designed to explore the safety and efficacy of IMC-1 for the treatment of patients with fibromyalgia.

Detailed Description

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Conditions

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Fibromyalgia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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IMC-1 Oral Tablet

2X IMC-1 Tablet taken orally, each morning and evening.

Group Type EXPERIMENTAL

IMC-1

Intervention Type DRUG

Patients will take 1 tablet twice daily, each morning and evening, of randomly assigned study drug orally starting on Day 1 through study duration.

Placebo

2X Placebo Tablet taken orally, each morning and evening.

Group Type PLACEBO_COMPARATOR

Placebo BID Tablet

Intervention Type DRUG

Patients will take 1 tablet twice daily, each morning and evening, of randomly assigned study drug orally starting on Day 1 through study duration.

Interventions

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IMC-1

Patients will take 1 tablet twice daily, each morning and evening, of randomly assigned study drug orally starting on Day 1 through study duration.

Intervention Type DRUG

Placebo BID Tablet

Patients will take 1 tablet twice daily, each morning and evening, of randomly assigned study drug orally starting on Day 1 through study duration.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* The patient is female, 18 to 65 years of age, inclusive.
* The patient has a diagnosis of primary FM as defined by the 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria (American College of Rheumatology Preliminary Diagnostic Criteria)
* The in clinic 7-day recall VAS scale average daily pain intensity score at Screening visit within protocol defined range.

Exclusion Criteria

* Any underlying medical or psychiatric condition that could impact their safe participation per protocol.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Virios Therapeutics, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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IMC Study Site

Birmingham, Alabama, United States

Site Status

IMC Study Site

Rogers, Arkansas, United States

Site Status

IMC Study Site

Oceanside, California, United States

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IMC Study Site

Riverside, California, United States

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IMC Study Site

Sacramento, California, United States

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IMC Study Site

San Diego, California, United States

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IMC Study Site

Santa Ana, California, United States

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IMC Study Site

Temecula, California, United States

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IMC Study Site

Jacksonville, Florida, United States

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IMC Study Site

Ocala, Florida, United States

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IMC Study Site

Oldsmar, Florida, United States

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IMC Study Site

Orlando, Florida, United States

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IMC Study Site

Tampa, Florida, United States

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IMC Study Site

Alpharetta, Georgia, United States

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IMC Study Site

Gurnee, Illinois, United States

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IMC Study Site

Evansville, Indiana, United States

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IMC Study Site

Des Moines, Iowa, United States

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IMC Study SIte

Prairie Village, Kansas, United States

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IMC Study Site

Covington, Louisiana, United States

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IMC Study Site

New Orleans, Louisiana, United States

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IMC Study Site

Prairieville, Louisiana, United States

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IMC Study Site

Boston, Massachusetts, United States

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IMC Study Site

North Dartmouth, Massachusetts, United States

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IMC Study Site

Jackson, Mississippi, United States

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IMC Study Site

Las Vegas, Nevada, United States

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IMC Study Site

Albuquerque, New Mexico, United States

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IMC Study Site

Cedarhurst, New York, United States

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IMC Study Site

Williamsville, New York, United States

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IMC Study Site

Cincinnati, Ohio, United States

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IMC Study Site

North Canton, Ohio, United States

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IMC Study Site

Oklahoma City, Oklahoma, United States

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IMC Study Site

Tulsa, Oklahoma, United States

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IMC Study Site

Portland, Oregon, United States

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IMC Study Site

Allentown, Pennsylvania, United States

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IMC Study Site

Warwick, Rhode Island, United States

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IMC Study Site

Chattanooga, Tennessee, United States

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IMC Study Site

Knoxville, Tennessee, United States

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IMC Study Site

Austin, Texas, United States

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IMC Study Site

Dallas, Texas, United States

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IMC Study Site

Salt Lake City, Utah, United States

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IMC Study Site

Charlottesville, Virginia, United States

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IMC Study Site

Everett, Washington, United States

Site Status

Countries

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United States

References

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Pridgen WL, Duffy C, Gendreau JF, Gendreau RM. A famciclovir + celecoxib combination treatment is safe and efficacious in the treatment of fibromyalgia. J Pain Res. 2017 Feb 22;10:451-460. doi: 10.2147/JPR.S127288. eCollection 2017.

Reference Type BACKGROUND
PMID: 28260944 (View on PubMed)

Other Identifiers

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PRID-202

Identifier Type: -

Identifier Source: org_study_id

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