A Study for Adult Patients With Fibromyalgia

NCT ID: NCT00965081

Last Updated: 2011-11-03

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

308 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2010-11-30

Brief Summary

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The main purpose of this study is to determine if 30 milligrams (mg) of duloxetine is effective in the treatment of fibromyalgia compared to placebo.

Detailed Description

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Conditions

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Fibromyalgia, Primary Fibromyalgia, Secondary

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Duloxetine

Group Type EXPERIMENTAL

Duloxetine

Intervention Type DRUG

30 milligrams (mg) dose daily (QD) by mouth (po) at the same time each day for 12 weeks

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

QD po at the same time each day for 12 weeks

Interventions

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Duloxetine

30 milligrams (mg) dose daily (QD) by mouth (po) at the same time each day for 12 weeks

Intervention Type DRUG

Placebo

QD po at the same time each day for 12 weeks

Intervention Type DRUG

Other Intervention Names

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Cymbalta LY248686

Eligibility Criteria

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Inclusion Criteria

* Meet study criteria for fibromyalgia diagnosis.

Exclusion Criteria

* Have previously or are currently taking duloxetine.
* Have been diagnosed with certain psychoses, bipolar or schizoaffective disorder
* Have pain symptoms that are difficult to differentiate from fibromyalgia.
* Have seizure disorder, uncontrolled narrow angle glaucoma, or acute liver injury (such as hepatitis) or severe cirrhosis.
* Have had any primary Axis 1 diagnosis other than major depressive disorder or generalized anxiety disorder within the past year.
* Are pregnant or breast-feeding
* Have a current or previous diagnosis of rheumatoid, infectious or inflammatory arthritis or an autoimmune disease
* Have a regional pain syndrome, failed back syndrome or chronic localized pan related to any past surgery
* Have a serious unstable medical illness
* Have a history of substance abuse or dependence within the past year
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Guadalajara, , Mexico

Site Status

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Mérida, , Mexico

Site Status

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Monterrey, , Mexico

Site Status

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Morelia, , Mexico

Site Status

Countries

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Mexico

Other Identifiers

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F1J-MC-HMGG

Identifier Type: OTHER

Identifier Source: secondary_id

12873

Identifier Type: -

Identifier Source: org_study_id